Retinoic acid induces functionally suppressive Foxp3+RORγt+ T cells in vitro
[Introduction]: CD4+ T cells with regulatory function co-expressing Foxp3 and RORγt are linked to the development of oral tolerance towards innocuous food antigens in mice. This study aimed to discern the role played by IL-6 and retinoic acid (RA) in the in vitro generation of Foxp3+RORγt+ T cells and to investigate whether such cells have suppressive properties.
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Main Authors: | , , , , , |
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Other Authors: | |
Format: | artículo biblioteca |
Language: | English |
Published: |
Frontiers Media
2021
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Online Access: | http://hdl.handle.net/10261/263380 http://dx.doi.org/10.13039/501100011033 http://dx.doi.org/10.13039/501100000780 |
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