Incidence of trypanasoma cruzi infection in two Guatemalan communities
The prevalence of human infection by Trypanosoma cruzi was assessed using an enzyme-linked immunosorbent assay (ELISA) in a serological survey in 1998 of 2 rural communities (SMH and PS) in Guatemala. In SMH (Department of Zacapa), where Rhodnius prolixuswas the principal vector, the seroprevalence amongst 373 people tested was 38 · 8%. In PS (Department of Santa Rosa), where the main vector was Triatoma dimidiata, 8 · 9% of the 428 people tested were seropositive. The overall prevalence of seropositivity was higher in females than in males in both SMH (40% vs 36%) and PS (11 · 9% vs 4 · 9%), although this difference was significant only in PS. Historical seroconversion rates, estimated retrospectively by fitting a transmission model to the age-prevalence curves, were 3 · 8% per year in SMH and 0 · 5% per year in PS. There was some indication of a recent reduction in incidence in both villages. In PS, but not in SMH, both the observed prevalence and the estimated incidence rates were significantly higher in females than in males.
| Main Authors: | , , , |
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| Format: | Texto biblioteca |
| Language: | eng |
| Subjects: | Trypanosoma cruzi, Tripanosomiasis, Enfermedad de chagas, Salud pública, Artfrosur, |
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