Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score

Abstract Background: Primary care physicians have difficulty dealing with patients who have HF with preserved LVEF(HFpEF). The prognosis of HFpEF is poor, and difficult to predict on primary care. Objective: The aim of the study is to apply the H2FPEF score to primary care patients and verify its power to assess the risk of death or hospitalization due to cardiovascular disease. Methods: This longitudinal study included 402 individuals, with signs or symptoms of HF, aged≥45 years and, underwent an evaluation which included clinical examination, BNP and echocardiogram. The diagnosis of HFpEF was confirmed by the criteria of the European Society of Cardiology. After five years, the patients were reassessed as to the occurrence of the composite outcome, death from any cause or hospitalization for cardiovascular disease. H2FPEF used six variables: body mass index, medications for hypertension, age, pulmonary artery systolic pressure, atrial fibrillation and E/e' ratio ranged from 0 to 9 points. The level of statistical significance was p<0.05. Results: HFpEF was diagnosed in 58(14.4%). Among patients with H2FPEF≥4, 30% had HFpEF and in those with a score≤4, HFpEF was present in 12%. Patients with HFpEF and H2FPEF≥4 had 53% of outcomes, whereas patients with HFpEF and a score ≤4 had a 21% of outcomes. BNP values were higher in patients with HFpEF compared to those without HFpEF(p<0.0001). Conclusion: H2FPEF≥4 indicated a worse prognosis in patients with HFpEF assisted in primary care. H2FPEF may be a simple and useful tool for risk stratification in patients with HFpEF at the primary care.

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Main Authors: Jorge,Antonio Jose Lagoeiro, Rosa,Maria Luiza Garcia, Martins,Wolney de Andrade, Leite,Adson, Correia,Dayse Mary da Silva, Saad,Maria Auxiliadora Nogueira, Villacorta,Humberto, Chermont,Sergio, Gismondi,Ronaldo Altenburg, Almeida,Breno Macedo, Mesquita,Evandro Tinoco
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Cardiologia 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000600666
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spelling oai:scielo:S2359-564720200006006662020-11-23Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF ScoreJorge,Antonio Jose LagoeiroRosa,Maria Luiza GarciaMartins,Wolney de AndradeLeite,AdsonCorreia,Dayse Mary da SilvaSaad,Maria Auxiliadora NogueiraVillacorta,HumbertoChermont,SergioGismondi,Ronaldo AltenburgAlmeida,Breno MacedoMesquita,Evandro Tinoco Heart Failure Stroke Volume Risk Assessment Morbidity Mortality H2FPEF Score Abstract Background: Primary care physicians have difficulty dealing with patients who have HF with preserved LVEF(HFpEF). The prognosis of HFpEF is poor, and difficult to predict on primary care. Objective: The aim of the study is to apply the H2FPEF score to primary care patients and verify its power to assess the risk of death or hospitalization due to cardiovascular disease. Methods: This longitudinal study included 402 individuals, with signs or symptoms of HF, aged≥45 years and, underwent an evaluation which included clinical examination, BNP and echocardiogram. The diagnosis of HFpEF was confirmed by the criteria of the European Society of Cardiology. After five years, the patients were reassessed as to the occurrence of the composite outcome, death from any cause or hospitalization for cardiovascular disease. H2FPEF used six variables: body mass index, medications for hypertension, age, pulmonary artery systolic pressure, atrial fibrillation and E/e' ratio ranged from 0 to 9 points. The level of statistical significance was p<0.05. Results: HFpEF was diagnosed in 58(14.4%). Among patients with H2FPEF≥4, 30% had HFpEF and in those with a score≤4, HFpEF was present in 12%. Patients with HFpEF and H2FPEF≥4 had 53% of outcomes, whereas patients with HFpEF and a score ≤4 had a 21% of outcomes. BNP values were higher in patients with HFpEF compared to those without HFpEF(p<0.0001). Conclusion: H2FPEF≥4 indicated a worse prognosis in patients with HFpEF assisted in primary care. H2FPEF may be a simple and useful tool for risk stratification in patients with HFpEF at the primary care.info:eu-repo/semantics/openAccessSociedade Brasileira de CardiologiaInternational Journal of Cardiovascular Sciences v.33 n.6 20202020-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000600666en10.36660/ijcs.20200076
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libraryname SciELO
language English
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author Jorge,Antonio Jose Lagoeiro
Rosa,Maria Luiza Garcia
Martins,Wolney de Andrade
Leite,Adson
Correia,Dayse Mary da Silva
Saad,Maria Auxiliadora Nogueira
Villacorta,Humberto
Chermont,Sergio
Gismondi,Ronaldo Altenburg
Almeida,Breno Macedo
Mesquita,Evandro Tinoco
spellingShingle Jorge,Antonio Jose Lagoeiro
Rosa,Maria Luiza Garcia
Martins,Wolney de Andrade
Leite,Adson
Correia,Dayse Mary da Silva
Saad,Maria Auxiliadora Nogueira
Villacorta,Humberto
Chermont,Sergio
Gismondi,Ronaldo Altenburg
Almeida,Breno Macedo
Mesquita,Evandro Tinoco
Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
author_facet Jorge,Antonio Jose Lagoeiro
Rosa,Maria Luiza Garcia
Martins,Wolney de Andrade
Leite,Adson
Correia,Dayse Mary da Silva
Saad,Maria Auxiliadora Nogueira
Villacorta,Humberto
Chermont,Sergio
Gismondi,Ronaldo Altenburg
Almeida,Breno Macedo
Mesquita,Evandro Tinoco
author_sort Jorge,Antonio Jose Lagoeiro
title Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
title_short Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
title_full Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
title_fullStr Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
title_full_unstemmed Prognosis of Heart Failure with Preserved Ejection Fraction in Primary Care by the H2FPEF Score
title_sort prognosis of heart failure with preserved ejection fraction in primary care by the h2fpef score
description Abstract Background: Primary care physicians have difficulty dealing with patients who have HF with preserved LVEF(HFpEF). The prognosis of HFpEF is poor, and difficult to predict on primary care. Objective: The aim of the study is to apply the H2FPEF score to primary care patients and verify its power to assess the risk of death or hospitalization due to cardiovascular disease. Methods: This longitudinal study included 402 individuals, with signs or symptoms of HF, aged≥45 years and, underwent an evaluation which included clinical examination, BNP and echocardiogram. The diagnosis of HFpEF was confirmed by the criteria of the European Society of Cardiology. After five years, the patients were reassessed as to the occurrence of the composite outcome, death from any cause or hospitalization for cardiovascular disease. H2FPEF used six variables: body mass index, medications for hypertension, age, pulmonary artery systolic pressure, atrial fibrillation and E/e' ratio ranged from 0 to 9 points. The level of statistical significance was p<0.05. Results: HFpEF was diagnosed in 58(14.4%). Among patients with H2FPEF≥4, 30% had HFpEF and in those with a score≤4, HFpEF was present in 12%. Patients with HFpEF and H2FPEF≥4 had 53% of outcomes, whereas patients with HFpEF and a score ≤4 had a 21% of outcomes. BNP values were higher in patients with HFpEF compared to those without HFpEF(p<0.0001). Conclusion: H2FPEF≥4 indicated a worse prognosis in patients with HFpEF assisted in primary care. H2FPEF may be a simple and useful tool for risk stratification in patients with HFpEF at the primary care.
publisher Sociedade Brasileira de Cardiologia
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000600666
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