Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.
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Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2022
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oai:scielo:S1984-825020220001008382023-01-05Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activityHuy,Roan Ngoc AnhGovindan,RamuSivaramakumar,NavanitaRaman,RajeshJayaraman,SaravananBasavan,DuraiswamyPalanisamy,Dhanabal S Calculi Litholytic Basella rubra Plant organs Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.58 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100838en10.1590/s2175-97902022e20582 |
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Huy,Roan Ngoc Anh Govindan,Ramu Sivaramakumar,Navanita Raman,Rajesh Jayaraman,Saravanan Basavan,Duraiswamy Palanisamy,Dhanabal S |
| spellingShingle |
Huy,Roan Ngoc Anh Govindan,Ramu Sivaramakumar,Navanita Raman,Rajesh Jayaraman,Saravanan Basavan,Duraiswamy Palanisamy,Dhanabal S Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| author_facet |
Huy,Roan Ngoc Anh Govindan,Ramu Sivaramakumar,Navanita Raman,Rajesh Jayaraman,Saravanan Basavan,Duraiswamy Palanisamy,Dhanabal S |
| author_sort |
Huy,Roan Ngoc Anh |
| title |
Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_short |
Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_full |
Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_fullStr |
Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_full_unstemmed |
Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_sort |
inhibition of calculi forming oxalate by dietary basella rubra organs: litholytic activity |
| description |
Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis. |
| publisher |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas |
| publishDate |
2022 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100838 |
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