Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez.
The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells.
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| Idioma: | English |
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Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2019
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oai:scielo:S1984-825020190001005932019-12-12Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez.Fabri,Natasha TiemiGatto,Larissa JunqueiraFurusho,Alethéia SantosGarcia,Meira Janette BallestrosMarques,Francisco de AssisMiguel,Marilis DallarmiMontrucchio,Deise PrehsZanin,Sandra Maria WarumbyMiguel,Obdulio GomesDias,Josiane de Fátima Gaspari Ocotea diospyrifolia Lauraceae Spathulenol Antioxidant Toxicity The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.55 20192019-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100593en10.1590/s2175-97902019000218471 |
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| country |
Brasil |
| countrycode |
BR |
| component |
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En linea |
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rev-scielo-br |
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revista |
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America del Sur |
| libraryname |
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| language |
English |
| format |
Digital |
| author |
Fabri,Natasha Tiemi Gatto,Larissa Junqueira Furusho,Alethéia Santos Garcia,Meira Janette Ballestros Marques,Francisco de Assis Miguel,Marilis Dallarmi Montrucchio,Deise Prehs Zanin,Sandra Maria Warumby Miguel,Obdulio Gomes Dias,Josiane de Fátima Gaspari |
| spellingShingle |
Fabri,Natasha Tiemi Gatto,Larissa Junqueira Furusho,Alethéia Santos Garcia,Meira Janette Ballestros Marques,Francisco de Assis Miguel,Marilis Dallarmi Montrucchio,Deise Prehs Zanin,Sandra Maria Warumby Miguel,Obdulio Gomes Dias,Josiane de Fátima Gaspari Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| author_facet |
Fabri,Natasha Tiemi Gatto,Larissa Junqueira Furusho,Alethéia Santos Garcia,Meira Janette Ballestros Marques,Francisco de Assis Miguel,Marilis Dallarmi Montrucchio,Deise Prehs Zanin,Sandra Maria Warumby Miguel,Obdulio Gomes Dias,Josiane de Fátima Gaspari |
| author_sort |
Fabri,Natasha Tiemi |
| title |
Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| title_short |
Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| title_full |
Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| title_fullStr |
Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| title_full_unstemmed |
Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. |
| title_sort |
composition, antioxidant properties, and biological activities of the essential oil extracted from ocotea diospyrifolia (meisn.) mez. |
| description |
The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were d-elemene, spathulenol, and b-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells. |
| publisher |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas |
| publishDate |
2019 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100593 |
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