Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia

ABSTRACT. The differential diagnosis of primary progressive aphasia (PPA) is challenging due to overlapping clinical manifestations of the different variants of the disease. This is particularly true for the logopenic variant of PPA (lvPPA), in which such overlap was reported with regard to impairments in repetition abilities. In this study, four individuals with lvPPA underwent standard neuropsychological and language assessments. The influence of psycholinguistic variables on their performance of in word, nonword and sentence repetition tasks was also specifically explored. Some level of heterogeneity was found in cognitive functions and in language. The four participants showed impairment in sentence repetition in which their performance was negatively affected by semantic reversibility and syntactic complexity. This study supports the heterogeneity of lvPPA with respect to the cognitive and linguistic status of participants. It also shows that sentence repetition is influenced not only by length, but also by semantic reversibility and syntactic complexity, two psycholinguistic variables known to place additional demands on phonological working memory.

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Main Authors: Macoir,Joel, Martel-Sauvageau,Vicent, Bouvier,Liziane, Laforce,Robert, Monetta,Laura
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000300405
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spelling oai:scielo:S1980-576420210003004052021-09-16Heterogeneity of repetition abilities in logopenic variant primary progressive aphasiaMacoir,JoelMartel-Sauvageau,VicentBouvier,LizianeLaforce,RobertMonetta,Laura primary progressive aphasia differential diagnosis acquired language disorders psycholinguistics ABSTRACT. The differential diagnosis of primary progressive aphasia (PPA) is challenging due to overlapping clinical manifestations of the different variants of the disease. This is particularly true for the logopenic variant of PPA (lvPPA), in which such overlap was reported with regard to impairments in repetition abilities. In this study, four individuals with lvPPA underwent standard neuropsychological and language assessments. The influence of psycholinguistic variables on their performance of in word, nonword and sentence repetition tasks was also specifically explored. Some level of heterogeneity was found in cognitive functions and in language. The four participants showed impairment in sentence repetition in which their performance was negatively affected by semantic reversibility and syntactic complexity. This study supports the heterogeneity of lvPPA with respect to the cognitive and linguistic status of participants. It also shows that sentence repetition is influenced not only by length, but also by semantic reversibility and syntactic complexity, two psycholinguistic variables known to place additional demands on phonological working memory.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.15 n.3 20212021-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000300405en10.1590/1980-57642021dn15-030014
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language English
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author Macoir,Joel
Martel-Sauvageau,Vicent
Bouvier,Liziane
Laforce,Robert
Monetta,Laura
spellingShingle Macoir,Joel
Martel-Sauvageau,Vicent
Bouvier,Liziane
Laforce,Robert
Monetta,Laura
Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
author_facet Macoir,Joel
Martel-Sauvageau,Vicent
Bouvier,Liziane
Laforce,Robert
Monetta,Laura
author_sort Macoir,Joel
title Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
title_short Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
title_full Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
title_fullStr Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
title_full_unstemmed Heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
title_sort heterogeneity of repetition abilities in logopenic variant primary progressive aphasia
description ABSTRACT. The differential diagnosis of primary progressive aphasia (PPA) is challenging due to overlapping clinical manifestations of the different variants of the disease. This is particularly true for the logopenic variant of PPA (lvPPA), in which such overlap was reported with regard to impairments in repetition abilities. In this study, four individuals with lvPPA underwent standard neuropsychological and language assessments. The influence of psycholinguistic variables on their performance of in word, nonword and sentence repetition tasks was also specifically explored. Some level of heterogeneity was found in cognitive functions and in language. The four participants showed impairment in sentence repetition in which their performance was negatively affected by semantic reversibility and syntactic complexity. This study supports the heterogeneity of lvPPA with respect to the cognitive and linguistic status of participants. It also shows that sentence repetition is influenced not only by length, but also by semantic reversibility and syntactic complexity, two psycholinguistic variables known to place additional demands on phonological working memory.
publisher Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000300405
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AT laforcerobert heterogeneityofrepetitionabilitiesinlogopenicvariantprimaryprogressiveaphasia
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