Primary Non-Hodgkins lymphoma of the parotid gland
Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.
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Language: | English |
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Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
2011
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oai:scielo:S1808-869420110005000172011-10-17Primary Non-Hodgkins lymphoma of the parotid glandDispenza,FrancescoCicero,GiuseppeMortellaro,GianlucaMarchese,DonatellaKulamarva,GauthamDispenza,Carlo lymphoma lymphoma non-hodgkin parotid neoplasms radiotherapy salivary glands Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.info:eu-repo/semantics/openAccessAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.77 n.5 20112011-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000500017en10.1590/S1808-86942011000500017 |
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Dispenza,Francesco Cicero,Giuseppe Mortellaro,Gianluca Marchese,Donatella Kulamarva,Gautham Dispenza,Carlo |
spellingShingle |
Dispenza,Francesco Cicero,Giuseppe Mortellaro,Gianluca Marchese,Donatella Kulamarva,Gautham Dispenza,Carlo Primary Non-Hodgkins lymphoma of the parotid gland |
author_facet |
Dispenza,Francesco Cicero,Giuseppe Mortellaro,Gianluca Marchese,Donatella Kulamarva,Gautham Dispenza,Carlo |
author_sort |
Dispenza,Francesco |
title |
Primary Non-Hodgkins lymphoma of the parotid gland |
title_short |
Primary Non-Hodgkins lymphoma of the parotid gland |
title_full |
Primary Non-Hodgkins lymphoma of the parotid gland |
title_fullStr |
Primary Non-Hodgkins lymphoma of the parotid gland |
title_full_unstemmed |
Primary Non-Hodgkins lymphoma of the parotid gland |
title_sort |
primary non-hodgkins lymphoma of the parotid gland |
description |
Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity. |
publisher |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
publishDate |
2011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000500017 |
work_keys_str_mv |
AT dispenzafrancesco primarynonhodgkinslymphomaoftheparotidgland AT cicerogiuseppe primarynonhodgkinslymphomaoftheparotidgland AT mortellarogianluca primarynonhodgkinslymphomaoftheparotidgland AT marchesedonatella primarynonhodgkinslymphomaoftheparotidgland AT kulamarvagautham primarynonhodgkinslymphomaoftheparotidgland AT dispenzacarlo primarynonhodgkinslymphomaoftheparotidgland |
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