Primary Non-Hodgkins lymphoma of the parotid gland

Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.

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Main Authors: Dispenza,Francesco, Cicero,Giuseppe, Mortellaro,Gianluca, Marchese,Donatella, Kulamarva,Gautham, Dispenza,Carlo
Format: Digital revista
Language:English
Published: Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. 2011
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000500017
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spelling oai:scielo:S1808-869420110005000172011-10-17Primary Non-Hodgkins lymphoma of the parotid glandDispenza,FrancescoCicero,GiuseppeMortellaro,GianlucaMarchese,DonatellaKulamarva,GauthamDispenza,Carlo lymphoma lymphoma non-hodgkin parotid neoplasms radiotherapy salivary glands Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.info:eu-repo/semantics/openAccessAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.77 n.5 20112011-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000500017en10.1590/S1808-86942011000500017
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Dispenza,Francesco
Cicero,Giuseppe
Mortellaro,Gianluca
Marchese,Donatella
Kulamarva,Gautham
Dispenza,Carlo
spellingShingle Dispenza,Francesco
Cicero,Giuseppe
Mortellaro,Gianluca
Marchese,Donatella
Kulamarva,Gautham
Dispenza,Carlo
Primary Non-Hodgkins lymphoma of the parotid gland
author_facet Dispenza,Francesco
Cicero,Giuseppe
Mortellaro,Gianluca
Marchese,Donatella
Kulamarva,Gautham
Dispenza,Carlo
author_sort Dispenza,Francesco
title Primary Non-Hodgkins lymphoma of the parotid gland
title_short Primary Non-Hodgkins lymphoma of the parotid gland
title_full Primary Non-Hodgkins lymphoma of the parotid gland
title_fullStr Primary Non-Hodgkins lymphoma of the parotid gland
title_full_unstemmed Primary Non-Hodgkins lymphoma of the parotid gland
title_sort primary non-hodgkins lymphoma of the parotid gland
description Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. AIM: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. METHODS: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. RESULTS: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. CONCLUSION: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.
publisher Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publishDate 2011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942011000500017
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AT marchesedonatella primarynonhodgkinslymphomaoftheparotidgland
AT kulamarvagautham primarynonhodgkinslymphomaoftheparotidgland
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