Salivary arginase activity after mechanical-chemical therapy

Salivary arginase activity after mechanical-chemical therapy

Abstract Introduction Salivary components can be used as biomarkers for diagnosing and monitoring oral diseases. There is evidence that one potential biomarker, arginase, is associated with the inflammatory processes of periodontal disease, and its enzymatic activity is reduced according to the improvement in the clinical parameters after treatment. Objective The present study aimed to evaluate the salivary arginase activity in gingivitis and periodontitis patients treated with full-mouth mechanical procedures combined with the adjunctive use of essential oils or chlorhexidine mouthwash, respectively. Material and method Twenty-six gingivitis and 16 periodontitis patients received complete periodontal examinations at the baseline and 3 months after therapy, in which the periodontal probing depth, clinical attachment loss, plaque index, and gingival index measurements were taken. At these same appointments, the salivary total protein level and salivary arginase activity were also established via spectrophotometry. Result There were improvements in all of the clinical parameters (p < 0.05) evaluated from the baseline to 3 months in both groups. In addition, the salivary arginase activity and total protein levels were reduced after the gingivitis treatment. Conclusion Similar to the clinical results, both therapeutic protocols positively affected the salivary arginase activity; however, further studies are necessary to clarify its potential as a salivary biomarker for periodontal monitoring.

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Main Authors: CASTRO,Marcos Vinícius Moreira de, CORTELLI,Sheila Cavalca, RODRIGUES,Edson, MORAES,Alexsander de, COSTA,Fernando Oliveira, MAXIMO,Priscila de Macedo, CORTELLI,José Roberto
Format: Digital revista
Language:English
Published: Universidade Estadual Paulista Júlio de Mesquita Filho 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772018000500261
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spelling oai:scielo:S1807-257720180005002612018-11-09Salivary arginase activity after mechanical-chemical therapyCASTRO,Marcos Vinícius Moreira deCORTELLI,Sheila CavalcaRODRIGUES,EdsonMORAES,Alexsander deCOSTA,Fernando OliveiraMAXIMO,Priscila de MacedoCORTELLI,José Roberto Arginase gingivitis periodontitis essential oils chlorhexidine Abstract Introduction Salivary components can be used as biomarkers for diagnosing and monitoring oral diseases. There is evidence that one potential biomarker, arginase, is associated with the inflammatory processes of periodontal disease, and its enzymatic activity is reduced according to the improvement in the clinical parameters after treatment. Objective The present study aimed to evaluate the salivary arginase activity in gingivitis and periodontitis patients treated with full-mouth mechanical procedures combined with the adjunctive use of essential oils or chlorhexidine mouthwash, respectively. Material and method Twenty-six gingivitis and 16 periodontitis patients received complete periodontal examinations at the baseline and 3 months after therapy, in which the periodontal probing depth, clinical attachment loss, plaque index, and gingival index measurements were taken. At these same appointments, the salivary total protein level and salivary arginase activity were also established via spectrophotometry. Result There were improvements in all of the clinical parameters (p < 0.05) evaluated from the baseline to 3 months in both groups. In addition, the salivary arginase activity and total protein levels were reduced after the gingivitis treatment. Conclusion Similar to the clinical results, both therapeutic protocols positively affected the salivary arginase activity; however, further studies are necessary to clarify its potential as a salivary biomarker for periodontal monitoring.info:eu-repo/semantics/openAccessUniversidade Estadual Paulista Júlio de Mesquita FilhoRevista de Odontologia da UNESP v.47 n.5 20182018-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772018000500261en10.1590/1807-2577.09118
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country Brasil
countrycode BR
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access En linea
databasecode rev-scielo-br
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libraryname SciELO
language English
format Digital
author CASTRO,Marcos Vinícius Moreira de
CORTELLI,Sheila Cavalca
RODRIGUES,Edson
MORAES,Alexsander de
COSTA,Fernando Oliveira
MAXIMO,Priscila de Macedo
CORTELLI,José Roberto
spellingShingle CASTRO,Marcos Vinícius Moreira de
CORTELLI,Sheila Cavalca
RODRIGUES,Edson
MORAES,Alexsander de
COSTA,Fernando Oliveira
MAXIMO,Priscila de Macedo
CORTELLI,José Roberto
Salivary arginase activity after mechanical-chemical therapy
author_facet CASTRO,Marcos Vinícius Moreira de
CORTELLI,Sheila Cavalca
RODRIGUES,Edson
MORAES,Alexsander de
COSTA,Fernando Oliveira
MAXIMO,Priscila de Macedo
CORTELLI,José Roberto
author_sort CASTRO,Marcos Vinícius Moreira de
title Salivary arginase activity after mechanical-chemical therapy
title_short Salivary arginase activity after mechanical-chemical therapy
title_full Salivary arginase activity after mechanical-chemical therapy
title_fullStr Salivary arginase activity after mechanical-chemical therapy
title_full_unstemmed Salivary arginase activity after mechanical-chemical therapy
title_sort salivary arginase activity after mechanical-chemical therapy
description Abstract Introduction Salivary components can be used as biomarkers for diagnosing and monitoring oral diseases. There is evidence that one potential biomarker, arginase, is associated with the inflammatory processes of periodontal disease, and its enzymatic activity is reduced according to the improvement in the clinical parameters after treatment. Objective The present study aimed to evaluate the salivary arginase activity in gingivitis and periodontitis patients treated with full-mouth mechanical procedures combined with the adjunctive use of essential oils or chlorhexidine mouthwash, respectively. Material and method Twenty-six gingivitis and 16 periodontitis patients received complete periodontal examinations at the baseline and 3 months after therapy, in which the periodontal probing depth, clinical attachment loss, plaque index, and gingival index measurements were taken. At these same appointments, the salivary total protein level and salivary arginase activity were also established via spectrophotometry. Result There were improvements in all of the clinical parameters (p < 0.05) evaluated from the baseline to 3 months in both groups. In addition, the salivary arginase activity and total protein levels were reduced after the gingivitis treatment. Conclusion Similar to the clinical results, both therapeutic protocols positively affected the salivary arginase activity; however, further studies are necessary to clarify its potential as a salivary biomarker for periodontal monitoring.
publisher Universidade Estadual Paulista Júlio de Mesquita Filho
publishDate 2018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772018000500261
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