Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series

ABSTRACT This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials-ReBEC; identifier: RBR-8j9kqy [http://www.ensaiosclinicos.gov.br])

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Bibliographic Details
Main Authors: Baldi,Bruno Guedes, Fabro,Alexandre Todorovic, Franco,Andreia Craveiro, Machado,Marília Helena C, Prudente,Robson Aparecido, Franco,Estefânia Thomé, Marrone,Sergio Ribeiro, Vale,Simone Alves do, Cezare,Talita Jacon, Moraes,Marcelo Padovani de Toledo, Ferreira,Eloara Vieira Machado, Albuquerque,André Luis Pereira, Sawamura,Marcio Valente Yamada, Tanni,Suzana Erico
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132022000300300
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