Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain
ABSTRACT BACKGROUND AND OBJECTIVES: Several pathophysiological mechanisms are involved in the genesis of neuropathic pain. However, available justifications for its onset are unsatisfying and do not explain the participation of nervi nervorum and nervi vasorum abnormalities on functional aberrations which characterize pain generated by injuries to the peripheral nervous system. There are evidences that nervi nervorum contribute to the development and justify many clinical findings and prophylactic, therapeutic and rehabilitation alternatives related to neuropathic pain. This study aimed at presenting a review of anatomic and functional studies and theories about their objectives and at giving examples of conditions in which nervi nervorum have markedly participated in neuropathic pain generation and maintenance. CONTENTS: Nervi nervorum are a set of unmyelinated or poorly myelinated fibers located in peripheral nerves sheaths which, among other functions, seem to participate in the transmission of evoked sensory information and in the environmental regulation of peripheral nervous system structures. CONCLUSION: Nervi nervorum structural and functional abnormalities may contribute to the onset, maintenance and worsening of neuropathic pain and "demodulatory" painful syndromes. Further studies, especially with the application of more specific and sensitive histological, biochemical and electrophysiological methods are necessary to clarify the realities of their biologies.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Brasileira para o Estudo da Dor
2016
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500005 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
oai:scielo:S1806-00132016000500005 |
|---|---|
| record_format |
ojs |
| spelling |
oai:scielo:S1806-001320160005000052016-09-22Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic painTeixeira,Manoel JacobsenAlmeida,Daniel BenzecryYeng,Lin Tchia Nervi nervorum Neuropathic pain Nociceptive pain Pathophysiology Peripheral nerves ABSTRACT BACKGROUND AND OBJECTIVES: Several pathophysiological mechanisms are involved in the genesis of neuropathic pain. However, available justifications for its onset are unsatisfying and do not explain the participation of nervi nervorum and nervi vasorum abnormalities on functional aberrations which characterize pain generated by injuries to the peripheral nervous system. There are evidences that nervi nervorum contribute to the development and justify many clinical findings and prophylactic, therapeutic and rehabilitation alternatives related to neuropathic pain. This study aimed at presenting a review of anatomic and functional studies and theories about their objectives and at giving examples of conditions in which nervi nervorum have markedly participated in neuropathic pain generation and maintenance. CONTENTS: Nervi nervorum are a set of unmyelinated or poorly myelinated fibers located in peripheral nerves sheaths which, among other functions, seem to participate in the transmission of evoked sensory information and in the environmental regulation of peripheral nervous system structures. CONCLUSION: Nervi nervorum structural and functional abnormalities may contribute to the onset, maintenance and worsening of neuropathic pain and "demodulatory" painful syndromes. Further studies, especially with the application of more specific and sensitive histological, biochemical and electrophysiological methods are necessary to clarify the realities of their biologies.info:eu-repo/semantics/openAccessSociedade Brasileira para o Estudo da DorRevista Dor v.17 suppl.1 20162016-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500005en10.5935/1806-0013.20160038 |
| institution |
SCIELO |
| collection |
OJS |
| country |
Brasil |
| countrycode |
BR |
| component |
Revista |
| access |
En linea |
| databasecode |
rev-scielo-br |
| tag |
revista |
| region |
America del Sur |
| libraryname |
SciELO |
| language |
English |
| format |
Digital |
| author |
Teixeira,Manoel Jacobsen Almeida,Daniel Benzecry Yeng,Lin Tchia |
| spellingShingle |
Teixeira,Manoel Jacobsen Almeida,Daniel Benzecry Yeng,Lin Tchia Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| author_facet |
Teixeira,Manoel Jacobsen Almeida,Daniel Benzecry Yeng,Lin Tchia |
| author_sort |
Teixeira,Manoel Jacobsen |
| title |
Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| title_short |
Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| title_full |
Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| title_fullStr |
Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| title_full_unstemmed |
Concept of acute neuropathic pain. The role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| title_sort |
concept of acute neuropathic pain. the role of nervi nervorum in the distinction between acute nociceptive and neuropathic pain |
| description |
ABSTRACT BACKGROUND AND OBJECTIVES: Several pathophysiological mechanisms are involved in the genesis of neuropathic pain. However, available justifications for its onset are unsatisfying and do not explain the participation of nervi nervorum and nervi vasorum abnormalities on functional aberrations which characterize pain generated by injuries to the peripheral nervous system. There are evidences that nervi nervorum contribute to the development and justify many clinical findings and prophylactic, therapeutic and rehabilitation alternatives related to neuropathic pain. This study aimed at presenting a review of anatomic and functional studies and theories about their objectives and at giving examples of conditions in which nervi nervorum have markedly participated in neuropathic pain generation and maintenance. CONTENTS: Nervi nervorum are a set of unmyelinated or poorly myelinated fibers located in peripheral nerves sheaths which, among other functions, seem to participate in the transmission of evoked sensory information and in the environmental regulation of peripheral nervous system structures. CONCLUSION: Nervi nervorum structural and functional abnormalities may contribute to the onset, maintenance and worsening of neuropathic pain and "demodulatory" painful syndromes. Further studies, especially with the application of more specific and sensitive histological, biochemical and electrophysiological methods are necessary to clarify the realities of their biologies. |
| publisher |
Sociedade Brasileira para o Estudo da Dor |
| publishDate |
2016 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500005 |
| work_keys_str_mv |
AT teixeiramanoeljacobsen conceptofacuteneuropathicpaintheroleofnervinervoruminthedistinctionbetweenacutenociceptiveandneuropathicpain AT almeidadanielbenzecry conceptofacuteneuropathicpaintheroleofnervinervoruminthedistinctionbetweenacutenociceptiveandneuropathicpain AT yenglintchia conceptofacuteneuropathicpaintheroleofnervinervoruminthedistinctionbetweenacutenociceptiveandneuropathicpain |
| _version_ |
1756430531006824448 |