Overactive bladder – 18 years – Part II
ABSTRACT Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics – pillars of the overactive bladder pharmacotherapy – started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning – as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder – 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder.
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Digital revista |
Idioma: | English |
Publicado: |
Sociedade Brasileira de Urologia
2016
|
Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000200199 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:scielo:S1677-55382016000200199 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1677-553820160002001992016-05-19Overactive bladder – 18 years – Part IITruzzi,Jose CarlosGomes,Cristiano MendesBezerra,Carlos A.Plata,Ivan MauricioCampos,JoseGarrido,Gustavo LuisAlmeida,Fernando G.Averbeck,Marcio AugustoFornari,AlexandreSalazar,AnibalDell’Oro,ArturoCintra,CaioSacomani,Carlos Alberto RicettoTapia,Juan PabloBrambila,EduardoLongo,Emilio MiguelRocha,Flavio TrigoCoutinho,FranciscoFavre,GabrielGarcia,José AntonioCastaño,JuanReyes,MiguelLeyton,Rodrigo EugenioFerreira,Ruiter SilvaDuran,SergioLópez,VandaReges,Ricardo Overactive Bladder Muscarinic Antagonists Beta-adrenergic agonists Botulinum Toxin Sacral neuromodulation Urodynamics ABSTRACT Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics – pillars of the overactive bladder pharmacotherapy – started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning – as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder – 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder.info:eu-repo/semantics/openAccessSociedade Brasileira de UrologiaInternational braz j urol v.42 n.2 20162016-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000200199en10.1590/S1677-5538.IBJU.2015.0367 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Truzzi,Jose Carlos Gomes,Cristiano Mendes Bezerra,Carlos A. Plata,Ivan Mauricio Campos,Jose Garrido,Gustavo Luis Almeida,Fernando G. Averbeck,Marcio Augusto Fornari,Alexandre Salazar,Anibal Dell’Oro,Arturo Cintra,Caio Sacomani,Carlos Alberto Ricetto Tapia,Juan Pablo Brambila,Eduardo Longo,Emilio Miguel Rocha,Flavio Trigo Coutinho,Francisco Favre,Gabriel Garcia,José Antonio Castaño,Juan Reyes,Miguel Leyton,Rodrigo Eugenio Ferreira,Ruiter Silva Duran,Sergio López,Vanda Reges,Ricardo |
spellingShingle |
Truzzi,Jose Carlos Gomes,Cristiano Mendes Bezerra,Carlos A. Plata,Ivan Mauricio Campos,Jose Garrido,Gustavo Luis Almeida,Fernando G. Averbeck,Marcio Augusto Fornari,Alexandre Salazar,Anibal Dell’Oro,Arturo Cintra,Caio Sacomani,Carlos Alberto Ricetto Tapia,Juan Pablo Brambila,Eduardo Longo,Emilio Miguel Rocha,Flavio Trigo Coutinho,Francisco Favre,Gabriel Garcia,José Antonio Castaño,Juan Reyes,Miguel Leyton,Rodrigo Eugenio Ferreira,Ruiter Silva Duran,Sergio López,Vanda Reges,Ricardo Overactive bladder – 18 years – Part II |
author_facet |
Truzzi,Jose Carlos Gomes,Cristiano Mendes Bezerra,Carlos A. Plata,Ivan Mauricio Campos,Jose Garrido,Gustavo Luis Almeida,Fernando G. Averbeck,Marcio Augusto Fornari,Alexandre Salazar,Anibal Dell’Oro,Arturo Cintra,Caio Sacomani,Carlos Alberto Ricetto Tapia,Juan Pablo Brambila,Eduardo Longo,Emilio Miguel Rocha,Flavio Trigo Coutinho,Francisco Favre,Gabriel Garcia,José Antonio Castaño,Juan Reyes,Miguel Leyton,Rodrigo Eugenio Ferreira,Ruiter Silva Duran,Sergio López,Vanda Reges,Ricardo |
author_sort |
Truzzi,Jose Carlos |
title |
Overactive bladder – 18 years – Part II |
title_short |
Overactive bladder – 18 years – Part II |
title_full |
Overactive bladder – 18 years – Part II |
title_fullStr |
Overactive bladder – 18 years – Part II |
title_full_unstemmed |
Overactive bladder – 18 years – Part II |
title_sort |
overactive bladder – 18 years – part ii |
description |
ABSTRACT Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics – pillars of the overactive bladder pharmacotherapy – started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning – as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder – 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder. |
publisher |
Sociedade Brasileira de Urologia |
publishDate |
2016 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000200199 |
work_keys_str_mv |
AT truzzijosecarlos overactivebladder18yearspartii AT gomescristianomendes overactivebladder18yearspartii AT bezerracarlosa overactivebladder18yearspartii AT plataivanmauricio overactivebladder18yearspartii AT camposjose overactivebladder18yearspartii AT garridogustavoluis overactivebladder18yearspartii AT almeidafernandog overactivebladder18yearspartii AT averbeckmarcioaugusto overactivebladder18yearspartii AT fornarialexandre overactivebladder18yearspartii AT salazaranibal overactivebladder18yearspartii AT delloroarturo overactivebladder18yearspartii AT cintracaio overactivebladder18yearspartii AT sacomanicarlosalbertoricetto overactivebladder18yearspartii AT tapiajuanpablo overactivebladder18yearspartii AT brambilaeduardo overactivebladder18yearspartii AT longoemiliomiguel overactivebladder18yearspartii AT rochaflaviotrigo overactivebladder18yearspartii AT coutinhofrancisco overactivebladder18yearspartii AT favregabriel overactivebladder18yearspartii AT garciajoseantonio overactivebladder18yearspartii AT castanojuan overactivebladder18yearspartii AT reyesmiguel overactivebladder18yearspartii AT leytonrodrigoeugenio overactivebladder18yearspartii AT ferreiraruitersilva overactivebladder18yearspartii AT duransergio overactivebladder18yearspartii AT lopezvanda overactivebladder18yearspartii AT regesricardo overactivebladder18yearspartii |
_version_ |
1756428193988870144 |