The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome

OBJECTIVES: to evaluate the impact of laser therapy on inter-twin discordance in twin-to-twin transfusion syndrome (TTTS). METHODS: biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and estimated fetal weight were prospectively collected during a five-year period (1999 to 2004). The inter-twin discordance was expressed as a percentage of the largest twin's measurements. The measurements were made the day before laser, twice following laser and after delivery. The mean values of discordance in measurements and in fetal weight were calculated. ANOVA was used to compare mean values. RESULTS: the mean (SD) discordance for BPD, HC, AC, FL and estimated fetal weight the day before laser were 8.53% (5.28), 8.75% (2.76), 16.19% (4.85), 12.92% (5.13) and 28.50% (6.46) respectively. At the at 2nd ultrasound assessment after surgery were 4.37% (3.55), 3.73% (2.71), 8.90% (4.42), 6.61% (4.99) and 19.11% (8.01) respectively; and at birth the weight discordance was 18.55% (8.74). There was a significant decrease in discordance for HC and AC for each ultrasound assessment. CONCLUSIONS: there was a decrease in fetal growth discordance following laser therapy in TTTS. These changes might be related to re-adaptation of blood flow following laser therapy.

Saved in:
Bibliographic Details
Main Authors: Sa,Renato A. Moreira de, Laurent,Salomon J., Takahashi,Yuichiro, Yamamoto,Masami, Ville,Yves
Format: Digital revista
Language:English
Published: Instituto de Medicina Integral Prof. Fernando Figueira 2005
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292005000300007
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S1519-38292005000300007
record_format ojs
spelling oai:scielo:S1519-382920050003000072005-11-18The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndromeSa,Renato A. Moreira deLaurent,Salomon J.Takahashi,YuichiroYamamoto,MasamiVille,Yves Fetal transfusion Laser coagulation Fetoscopy OBJECTIVES: to evaluate the impact of laser therapy on inter-twin discordance in twin-to-twin transfusion syndrome (TTTS). METHODS: biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and estimated fetal weight were prospectively collected during a five-year period (1999 to 2004). The inter-twin discordance was expressed as a percentage of the largest twin's measurements. The measurements were made the day before laser, twice following laser and after delivery. The mean values of discordance in measurements and in fetal weight were calculated. ANOVA was used to compare mean values. RESULTS: the mean (SD) discordance for BPD, HC, AC, FL and estimated fetal weight the day before laser were 8.53% (5.28), 8.75% (2.76), 16.19% (4.85), 12.92% (5.13) and 28.50% (6.46) respectively. At the at 2nd ultrasound assessment after surgery were 4.37% (3.55), 3.73% (2.71), 8.90% (4.42), 6.61% (4.99) and 19.11% (8.01) respectively; and at birth the weight discordance was 18.55% (8.74). There was a significant decrease in discordance for HC and AC for each ultrasound assessment. CONCLUSIONS: there was a decrease in fetal growth discordance following laser therapy in TTTS. These changes might be related to re-adaptation of blood flow following laser therapy.info:eu-repo/semantics/openAccessInstituto de Medicina Integral Prof. Fernando FigueiraRevista Brasileira de Saúde Materno Infantil v.5 n.3 20052005-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292005000300007en10.1590/S1519-38292005000300007
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Sa,Renato A. Moreira de
Laurent,Salomon J.
Takahashi,Yuichiro
Yamamoto,Masami
Ville,Yves
spellingShingle Sa,Renato A. Moreira de
Laurent,Salomon J.
Takahashi,Yuichiro
Yamamoto,Masami
Ville,Yves
The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
author_facet Sa,Renato A. Moreira de
Laurent,Salomon J.
Takahashi,Yuichiro
Yamamoto,Masami
Ville,Yves
author_sort Sa,Renato A. Moreira de
title The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
title_short The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
title_full The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
title_fullStr The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
title_full_unstemmed The impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
title_sort impact of laser therapy on fetal growth discordance in twin-to-twin transfusion syndrome
description OBJECTIVES: to evaluate the impact of laser therapy on inter-twin discordance in twin-to-twin transfusion syndrome (TTTS). METHODS: biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and estimated fetal weight were prospectively collected during a five-year period (1999 to 2004). The inter-twin discordance was expressed as a percentage of the largest twin's measurements. The measurements were made the day before laser, twice following laser and after delivery. The mean values of discordance in measurements and in fetal weight were calculated. ANOVA was used to compare mean values. RESULTS: the mean (SD) discordance for BPD, HC, AC, FL and estimated fetal weight the day before laser were 8.53% (5.28), 8.75% (2.76), 16.19% (4.85), 12.92% (5.13) and 28.50% (6.46) respectively. At the at 2nd ultrasound assessment after surgery were 4.37% (3.55), 3.73% (2.71), 8.90% (4.42), 6.61% (4.99) and 19.11% (8.01) respectively; and at birth the weight discordance was 18.55% (8.74). There was a significant decrease in discordance for HC and AC for each ultrasound assessment. CONCLUSIONS: there was a decrease in fetal growth discordance following laser therapy in TTTS. These changes might be related to re-adaptation of blood flow following laser therapy.
publisher Instituto de Medicina Integral Prof. Fernando Figueira
publishDate 2005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292005000300007
work_keys_str_mv AT sarenatoamoreirade theimpactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT laurentsalomonj theimpactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT takahashiyuichiro theimpactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT yamamotomasami theimpactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT villeyves theimpactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT sarenatoamoreirade impactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT laurentsalomonj impactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT takahashiyuichiro impactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT yamamotomasami impactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
AT villeyves impactoflasertherapyonfetalgrowthdiscordanceintwintotwintransfusionsyndrome
_version_ 1756425908371062784