Resistant bacteria in stem cell transplant recipients
Bacterial infections account for most infections in hematopoietic stem cell transplant recipients. While early mortality reduced dramatically with the introduction of the concept of empirical antibiotic therapy in neutropenic patients, no effect of prophylaxis on the mortality was observed in many studies. On the other hand, antibiotic prophylaxis has resulted in the emergence of resistance among bacteria. In addition, the choice of the antibiotic regimen for empirical therapy and the practices of antibiotic therapy during neutropenia may result in a significant shift in the pattern of bacterial infections. The use of quinolones and vancomycin as prophylaxis, and of carbapenems and vancomycin in the empirical antibiotic therapy, are associated with the appearance of resistant Gram-positive and Gram-negative bacteria. Therefore, hematologists must be aware of the impact of these practices on the emergence of infections due to multi-resistant pathogens, since these infections may be associated with increased mortality.
Autor principal: | Nucci,Marcio |
---|---|
Formato: | Digital revista |
Idioma: | English |
Publicado: |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
2002
|
Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842002000300009 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Factors associated with bacteremia due to multidrug-resistant Gram-negative bacilli in hematopoietic stem cell transplant recipients
por: Garnica,M., et al.
Publicado: (2009) -
Difficulties in the revaccination program of hematopoietic stem cell transplantation recipients
por: Silva,Paula Moreira da, et al.
Publicado: (2017) -
Disseminated Fusarium infection in autologous stem cell transplant recipient
por: Avelino-Silva,Vivian Iida, et al.
Publicado: (2015) -
CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations
por: Takahashi,Hiroshi, et al.
Publicado: (2015) -
Quality of life and changes in the social dimension of hematopoietic stem cell transplants recipients
por: Machado,Celina Angélica Mattos, et al.
Publicado: (2021)