Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men
CONTEXT AND OBJECTIVE: The thickness of the carotid intima-media complex (C-IMC) is considered to be a marker of early atherosclerosis, but visual and echogenic changes to the C-IMC can also be noted. The objective here was to evaluate the relationship between cardiovascular risk factors and the echogenicity of the C-IMC and identify those most associated with an "abnormal" C-IMC. DESIGN AND SETTING: Cross-sectional study in the ultrasound sector of the Department of Diagnostic Imaging, Universidade Federal de São Paulo. METHODS: Eighty men were evaluated. Measurements of arterial blood pressure, waist circumference (WC), lipid profile, fasting glucose, uric acid and high-sensitivity C-reactive protein were obtained. The thickness of the C-IMC was measured by means of B-mode ultrasound, and the intima-media gray-scale mean (IM-GSM) and standard deviation (IM-SD) were calculated. RESULTS: The following were discriminating variables: fasting glucose (r2 = 0.036; P = 0.013), uric acid (r2 = 0.08; P = 0.03), IM-SD (r2 = 0.43; P < 0.001), IM-GSM (r2 = 0.35; P < 0.001) and thickness of the C-IMC (r2 = 0.29; P < 0.001). IM-GSM showed significant correlations with WC (r = -0.22; P = 0.005), fasting glucose (r = -0.24; P = 0.002) and high-density lipoprotein cholesterol (HDL-C) (r = 0.27; P = 0.0007). CONCLUSION: IM-GSM showed correlations with WC, fasting glucose and HDL-C. However, uric acid and IM-SD presented the greatest discriminating impact. These results suggest that visual changes in C-IMC may help identify patients with potential cardiovascular risk, independently of the thickness of the C-IMC.
Main Authors: | , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Associação Paulista de Medicina - APM
2014
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802014000200097 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S1516-31802014000200097 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1516-318020140002000972014-03-31Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in menSarmento,Priscilla Lopes da Fonseca AbrantesPlavnik,Frida LianeScaciota,AndreaLima,Joab OliveiraMiranda,Robson BarbosaAjzen,Sergio Aron Ultrasonography Carotid intima-media thickness Atherosclerosis Risk factors Metabolic syndrome X CONTEXT AND OBJECTIVE: The thickness of the carotid intima-media complex (C-IMC) is considered to be a marker of early atherosclerosis, but visual and echogenic changes to the C-IMC can also be noted. The objective here was to evaluate the relationship between cardiovascular risk factors and the echogenicity of the C-IMC and identify those most associated with an "abnormal" C-IMC. DESIGN AND SETTING: Cross-sectional study in the ultrasound sector of the Department of Diagnostic Imaging, Universidade Federal de São Paulo. METHODS: Eighty men were evaluated. Measurements of arterial blood pressure, waist circumference (WC), lipid profile, fasting glucose, uric acid and high-sensitivity C-reactive protein were obtained. The thickness of the C-IMC was measured by means of B-mode ultrasound, and the intima-media gray-scale mean (IM-GSM) and standard deviation (IM-SD) were calculated. RESULTS: The following were discriminating variables: fasting glucose (r2 = 0.036; P = 0.013), uric acid (r2 = 0.08; P = 0.03), IM-SD (r2 = 0.43; P < 0.001), IM-GSM (r2 = 0.35; P < 0.001) and thickness of the C-IMC (r2 = 0.29; P < 0.001). IM-GSM showed significant correlations with WC (r = -0.22; P = 0.005), fasting glucose (r = -0.24; P = 0.002) and high-density lipoprotein cholesterol (HDL-C) (r = 0.27; P = 0.0007). CONCLUSION: IM-GSM showed correlations with WC, fasting glucose and HDL-C. However, uric acid and IM-SD presented the greatest discriminating impact. These results suggest that visual changes in C-IMC may help identify patients with potential cardiovascular risk, independently of the thickness of the C-IMC. info:eu-repo/semantics/openAccessAssociação Paulista de Medicina - APMSao Paulo Medical Journal v.132 n.2 20142014-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802014000200097en10.1590/1516-3180.2014.1322490 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Sarmento,Priscilla Lopes da Fonseca Abrantes Plavnik,Frida Liane Scaciota,Andrea Lima,Joab Oliveira Miranda,Robson Barbosa Ajzen,Sergio Aron |
spellingShingle |
Sarmento,Priscilla Lopes da Fonseca Abrantes Plavnik,Frida Liane Scaciota,Andrea Lima,Joab Oliveira Miranda,Robson Barbosa Ajzen,Sergio Aron Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
author_facet |
Sarmento,Priscilla Lopes da Fonseca Abrantes Plavnik,Frida Liane Scaciota,Andrea Lima,Joab Oliveira Miranda,Robson Barbosa Ajzen,Sergio Aron |
author_sort |
Sarmento,Priscilla Lopes da Fonseca Abrantes |
title |
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
title_short |
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
title_full |
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
title_fullStr |
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
title_full_unstemmed |
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
title_sort |
relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men |
description |
CONTEXT AND OBJECTIVE: The thickness of the carotid intima-media complex (C-IMC) is considered to be a marker of early atherosclerosis, but visual and echogenic changes to the C-IMC can also be noted. The objective here was to evaluate the relationship between cardiovascular risk factors and the echogenicity of the C-IMC and identify those most associated with an "abnormal" C-IMC. DESIGN AND SETTING: Cross-sectional study in the ultrasound sector of the Department of Diagnostic Imaging, Universidade Federal de São Paulo. METHODS: Eighty men were evaluated. Measurements of arterial blood pressure, waist circumference (WC), lipid profile, fasting glucose, uric acid and high-sensitivity C-reactive protein were obtained. The thickness of the C-IMC was measured by means of B-mode ultrasound, and the intima-media gray-scale mean (IM-GSM) and standard deviation (IM-SD) were calculated. RESULTS: The following were discriminating variables: fasting glucose (r2 = 0.036; P = 0.013), uric acid (r2 = 0.08; P = 0.03), IM-SD (r2 = 0.43; P < 0.001), IM-GSM (r2 = 0.35; P < 0.001) and thickness of the C-IMC (r2 = 0.29; P < 0.001). IM-GSM showed significant correlations with WC (r = -0.22; P = 0.005), fasting glucose (r = -0.24; P = 0.002) and high-density lipoprotein cholesterol (HDL-C) (r = 0.27; P = 0.0007). CONCLUSION: IM-GSM showed correlations with WC, fasting glucose and HDL-C. However, uric acid and IM-SD presented the greatest discriminating impact. These results suggest that visual changes in C-IMC may help identify patients with potential cardiovascular risk, independently of the thickness of the C-IMC. |
publisher |
Associação Paulista de Medicina - APM |
publishDate |
2014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802014000200097 |
work_keys_str_mv |
AT sarmentopriscillalopesdafonsecaabrantes relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen AT plavnikfridaliane relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen AT scaciotaandrea relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen AT limajoaboliveira relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen AT mirandarobsonbarbosa relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen AT ajzensergioaron relationshipbetweencardiovascularriskfactorsandtheechogenicityandpatternofthecarotidintimamediacomplexinmen |
_version_ |
1756421595445854208 |