Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study

CONTEXT AND OBJECTIVE: Viral hepatitis A is still a concern at public health level in Brazil and around the world, due both to the number of affected subjects and the possibility of complications in the acute forms. The Brazilian Ministry of Health estimates that at least 70% of this country's population has already had contact with the hepatitis A virus (HAV). The aim here was to discover the prevalence of serological markers for the hepatitis A virus among children and teenagers at daycare facilities, kindergartens and elementary schools in the city of Santos. DESIGN AND SETTING: Cross-sectional study in kindergartens and elementary schools within the municipal education network in several regions of the city of Santos. METHOD: Students' family members were surveyed using a questionnaire and 4,680 finger-prick blood samples were taken and assayed by means of the ELISA technique. RESULTS: The general prevalence of anti-HAV IgG was 9.72% and, of these cases, 74.6% were reactive to anti-HAV IgM. There was higher prevalence of anti-HAV IgG among older children, females, children who played in streams, those whose homes were not connected to the sewage system, those whose parents had low education levels, those with low household income and those who did not live along the seashore. The prevalence of anti-HAV IgM peaked in the early years and subsequently fell, and it was lower on the hills and in the Northwestern Zone. CONCLUSION: The general prevalence of serological markers for hepatitis A was low in Santos.

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Main Authors: Ciaccia,Maria Célia Cunha, Moreira,Regina Célia, Ferraro,Alexandre Archanjo, Lemos,Marcílio Figueiredo, Oba,Isabel Takano, Porta,Gilda
Format: Digital revista
Language:English
Published: Associação Paulista de Medicina - APM 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802012000400005
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spelling oai:scielo:S1516-318020120004000052012-09-04Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional studyCiaccia,Maria Célia CunhaMoreira,Regina CéliaFerraro,Alexandre ArchanjoLemos,Marcílio FigueiredoOba,Isabel TakanoPorta,Gilda Prevalence Hepatitis A Child Serology Epidemiology CONTEXT AND OBJECTIVE: Viral hepatitis A is still a concern at public health level in Brazil and around the world, due both to the number of affected subjects and the possibility of complications in the acute forms. The Brazilian Ministry of Health estimates that at least 70% of this country's population has already had contact with the hepatitis A virus (HAV). The aim here was to discover the prevalence of serological markers for the hepatitis A virus among children and teenagers at daycare facilities, kindergartens and elementary schools in the city of Santos. DESIGN AND SETTING: Cross-sectional study in kindergartens and elementary schools within the municipal education network in several regions of the city of Santos. METHOD: Students' family members were surveyed using a questionnaire and 4,680 finger-prick blood samples were taken and assayed by means of the ELISA technique. RESULTS: The general prevalence of anti-HAV IgG was 9.72% and, of these cases, 74.6% were reactive to anti-HAV IgM. There was higher prevalence of anti-HAV IgG among older children, females, children who played in streams, those whose homes were not connected to the sewage system, those whose parents had low education levels, those with low household income and those who did not live along the seashore. The prevalence of anti-HAV IgM peaked in the early years and subsequently fell, and it was lower on the hills and in the Northwestern Zone. CONCLUSION: The general prevalence of serological markers for hepatitis A was low in Santos.info:eu-repo/semantics/openAccessAssociação Paulista de Medicina - APMSao Paulo Medical Journal v.130 n.4 20122012-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802012000400005en10.1590/S1516-31802012000400005
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libraryname SciELO
language English
format Digital
author Ciaccia,Maria Célia Cunha
Moreira,Regina Célia
Ferraro,Alexandre Archanjo
Lemos,Marcílio Figueiredo
Oba,Isabel Takano
Porta,Gilda
spellingShingle Ciaccia,Maria Célia Cunha
Moreira,Regina Célia
Ferraro,Alexandre Archanjo
Lemos,Marcílio Figueiredo
Oba,Isabel Takano
Porta,Gilda
Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
author_facet Ciaccia,Maria Célia Cunha
Moreira,Regina Célia
Ferraro,Alexandre Archanjo
Lemos,Marcílio Figueiredo
Oba,Isabel Takano
Porta,Gilda
author_sort Ciaccia,Maria Célia Cunha
title Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
title_short Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
title_full Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
title_fullStr Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
title_full_unstemmed Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
title_sort epidemiological and serological aspects of hepatitis a among children and teenagers in the city of santos: a cross-sectional study
description CONTEXT AND OBJECTIVE: Viral hepatitis A is still a concern at public health level in Brazil and around the world, due both to the number of affected subjects and the possibility of complications in the acute forms. The Brazilian Ministry of Health estimates that at least 70% of this country's population has already had contact with the hepatitis A virus (HAV). The aim here was to discover the prevalence of serological markers for the hepatitis A virus among children and teenagers at daycare facilities, kindergartens and elementary schools in the city of Santos. DESIGN AND SETTING: Cross-sectional study in kindergartens and elementary schools within the municipal education network in several regions of the city of Santos. METHOD: Students' family members were surveyed using a questionnaire and 4,680 finger-prick blood samples were taken and assayed by means of the ELISA technique. RESULTS: The general prevalence of anti-HAV IgG was 9.72% and, of these cases, 74.6% were reactive to anti-HAV IgM. There was higher prevalence of anti-HAV IgG among older children, females, children who played in streams, those whose homes were not connected to the sewage system, those whose parents had low education levels, those with low household income and those who did not live along the seashore. The prevalence of anti-HAV IgM peaked in the early years and subsequently fell, and it was lower on the hills and in the Northwestern Zone. CONCLUSION: The general prevalence of serological markers for hepatitis A was low in Santos.
publisher Associação Paulista de Medicina - APM
publishDate 2012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802012000400005
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