Primary malignancy in giant cell tumor: a case report
CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does. CASE REPORT: This report presents the case of a 39-year-old female with pain in her left shoulder for one month. Radiography showed a pathological fracture of the proximal humerus associated with an osteolytic lesion. Histopathological analysis showed typical areas of GCT juxtaposed with a sarcomatous component. CONCLUSIONS: PMGCT seems to behave less aggressively than secondary malignancy in GCT, and it may simulate its more common benign counterpart clinically and radiographically. However, it requires a more aggressive type of treatment.
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Associação Paulista de Medicina - APM
2009
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oai:scielo:S1516-318020090005000112010-02-03Primary malignancy in giant cell tumor: a case reportBispo Júnior,Rosalvo ZósimoCamargo,Olavo Pires deIda,Cristiane MarieBaptista,André MathiasRibeiro,Marcelo BarbosaBruno,José MarcelloOliveira,Cláudia Regina Gomes Cardim Mendes de Bone neoplasms Bone tissue Giant cell tumor of bone Osteosarcoma Histiocytoma, malignant fibrous CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does. CASE REPORT: This report presents the case of a 39-year-old female with pain in her left shoulder for one month. Radiography showed a pathological fracture of the proximal humerus associated with an osteolytic lesion. Histopathological analysis showed typical areas of GCT juxtaposed with a sarcomatous component. CONCLUSIONS: PMGCT seems to behave less aggressively than secondary malignancy in GCT, and it may simulate its more common benign counterpart clinically and radiographically. However, it requires a more aggressive type of treatment.info:eu-repo/semantics/openAccessAssociação Paulista de Medicina - APMSao Paulo Medical Journal v.127 n.5 20092009-09-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500011en10.1590/S1516-31802009000500011 |
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Bispo Júnior,Rosalvo Zósimo Camargo,Olavo Pires de Ida,Cristiane Marie Baptista,André Mathias Ribeiro,Marcelo Barbosa Bruno,José Marcello Oliveira,Cláudia Regina Gomes Cardim Mendes de |
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Bispo Júnior,Rosalvo Zósimo Camargo,Olavo Pires de Ida,Cristiane Marie Baptista,André Mathias Ribeiro,Marcelo Barbosa Bruno,José Marcello Oliveira,Cláudia Regina Gomes Cardim Mendes de Primary malignancy in giant cell tumor: a case report |
| author_facet |
Bispo Júnior,Rosalvo Zósimo Camargo,Olavo Pires de Ida,Cristiane Marie Baptista,André Mathias Ribeiro,Marcelo Barbosa Bruno,José Marcello Oliveira,Cláudia Regina Gomes Cardim Mendes de |
| author_sort |
Bispo Júnior,Rosalvo Zósimo |
| title |
Primary malignancy in giant cell tumor: a case report |
| title_short |
Primary malignancy in giant cell tumor: a case report |
| title_full |
Primary malignancy in giant cell tumor: a case report |
| title_fullStr |
Primary malignancy in giant cell tumor: a case report |
| title_full_unstemmed |
Primary malignancy in giant cell tumor: a case report |
| title_sort |
primary malignancy in giant cell tumor: a case report |
| description |
CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does. CASE REPORT: This report presents the case of a 39-year-old female with pain in her left shoulder for one month. Radiography showed a pathological fracture of the proximal humerus associated with an osteolytic lesion. Histopathological analysis showed typical areas of GCT juxtaposed with a sarcomatous component. CONCLUSIONS: PMGCT seems to behave less aggressively than secondary malignancy in GCT, and it may simulate its more common benign counterpart clinically and radiographically. However, it requires a more aggressive type of treatment. |
| publisher |
Associação Paulista de Medicina - APM |
| publishDate |
2009 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500011 |
| work_keys_str_mv |
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| _version_ |
1756421543613693952 |