Comparative study of etiological diagnosis of nosocomial pneumonia

Nosocomial pneumonia is a common complication in patients on mechanical ventilation and results in significant mortality. Diagnosis of pneumonia in patients who are intubated and under mechanical ventilation is difficult, even with the aid of clinical, laboratorial, and endoscopic tests. The objective of this study was to compare three methods of tracheal sputum collection in patients with a clinical and radiological diagnosis of pneumonia. Twenty-two patients with a clinical diagnosis of liver disease were enrolled, 18 years of age or older, 13 males and nine females, who had been mechanically ventilated over an intubation period of 5.86 ± 4.62 days. These patients were being treated in intensive care unit (ICU) of the Liver Transplantdepartment. Secretion collection was carried out according to a protocol with three distinct methods: endotracheal aspiration with a closed aspiration system, Bal cath and bronchoalveolar lavage. Of the 22 patients analyzed, 21 (95.4%) showed one or more infectious agent when the closed aspiration system was used. With the Bal cathâ collection, 19 patients (86.3%) had one or more infectious agents; in the collection by bronchoalveolar lavage, 10 patients (45.4%) presented one or more infectious agent. According to the laboratorial analysis, 14 different microorganisms were isolated, the most frequent of which were Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. We concluded that aspiration with the closed system produced the most effective results in comparison with those of bronchoalveolar lavage and the Bal cathâ, and may be an acceptable method for diagnosing hospital-acquired pneumonia when no fiberoptic technique is available.

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Main Authors: Carvalho,Eliane Maria de, Massarollo,Paulo Celso Bosco, Levin,Anna S., Isern,Maria Rita Montenegro, Pereira,Wilson Leite, Abdala,Edson, Rossi,Flavia, Mies,Sérgio
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2008
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100015
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spelling oai:scielo:S1413-867020080001000152008-06-05Comparative study of etiological diagnosis of nosocomial pneumoniaCarvalho,Eliane Maria deMassarollo,Paulo Celso BoscoLevin,Anna S.Isern,Maria Rita MontenegroPereira,Wilson LeiteAbdala,EdsonRossi,FlaviaMies,Sérgio Pneumonia microorganisms bronchoalveolar lavage tracheal aspiration closed aspiration system Nosocomial pneumonia is a common complication in patients on mechanical ventilation and results in significant mortality. Diagnosis of pneumonia in patients who are intubated and under mechanical ventilation is difficult, even with the aid of clinical, laboratorial, and endoscopic tests. The objective of this study was to compare three methods of tracheal sputum collection in patients with a clinical and radiological diagnosis of pneumonia. Twenty-two patients with a clinical diagnosis of liver disease were enrolled, 18 years of age or older, 13 males and nine females, who had been mechanically ventilated over an intubation period of 5.86 ± 4.62 days. These patients were being treated in intensive care unit (ICU) of the Liver Transplantdepartment. Secretion collection was carried out according to a protocol with three distinct methods: endotracheal aspiration with a closed aspiration system, Bal cath and bronchoalveolar lavage. Of the 22 patients analyzed, 21 (95.4%) showed one or more infectious agent when the closed aspiration system was used. With the Bal cathâ collection, 19 patients (86.3%) had one or more infectious agents; in the collection by bronchoalveolar lavage, 10 patients (45.4%) presented one or more infectious agent. According to the laboratorial analysis, 14 different microorganisms were isolated, the most frequent of which were Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. We concluded that aspiration with the closed system produced the most effective results in comparison with those of bronchoalveolar lavage and the Bal cathâ, and may be an acceptable method for diagnosing hospital-acquired pneumonia when no fiberoptic technique is available.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.12 n.1 20082008-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100015en10.1590/S1413-86702008000100015
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language English
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author Carvalho,Eliane Maria de
Massarollo,Paulo Celso Bosco
Levin,Anna S.
Isern,Maria Rita Montenegro
Pereira,Wilson Leite
Abdala,Edson
Rossi,Flavia
Mies,Sérgio
spellingShingle Carvalho,Eliane Maria de
Massarollo,Paulo Celso Bosco
Levin,Anna S.
Isern,Maria Rita Montenegro
Pereira,Wilson Leite
Abdala,Edson
Rossi,Flavia
Mies,Sérgio
Comparative study of etiological diagnosis of nosocomial pneumonia
author_facet Carvalho,Eliane Maria de
Massarollo,Paulo Celso Bosco
Levin,Anna S.
Isern,Maria Rita Montenegro
Pereira,Wilson Leite
Abdala,Edson
Rossi,Flavia
Mies,Sérgio
author_sort Carvalho,Eliane Maria de
title Comparative study of etiological diagnosis of nosocomial pneumonia
title_short Comparative study of etiological diagnosis of nosocomial pneumonia
title_full Comparative study of etiological diagnosis of nosocomial pneumonia
title_fullStr Comparative study of etiological diagnosis of nosocomial pneumonia
title_full_unstemmed Comparative study of etiological diagnosis of nosocomial pneumonia
title_sort comparative study of etiological diagnosis of nosocomial pneumonia
description Nosocomial pneumonia is a common complication in patients on mechanical ventilation and results in significant mortality. Diagnosis of pneumonia in patients who are intubated and under mechanical ventilation is difficult, even with the aid of clinical, laboratorial, and endoscopic tests. The objective of this study was to compare three methods of tracheal sputum collection in patients with a clinical and radiological diagnosis of pneumonia. Twenty-two patients with a clinical diagnosis of liver disease were enrolled, 18 years of age or older, 13 males and nine females, who had been mechanically ventilated over an intubation period of 5.86 ± 4.62 days. These patients were being treated in intensive care unit (ICU) of the Liver Transplantdepartment. Secretion collection was carried out according to a protocol with three distinct methods: endotracheal aspiration with a closed aspiration system, Bal cath and bronchoalveolar lavage. Of the 22 patients analyzed, 21 (95.4%) showed one or more infectious agent when the closed aspiration system was used. With the Bal cathâ collection, 19 patients (86.3%) had one or more infectious agents; in the collection by bronchoalveolar lavage, 10 patients (45.4%) presented one or more infectious agent. According to the laboratorial analysis, 14 different microorganisms were isolated, the most frequent of which were Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. We concluded that aspiration with the closed system produced the most effective results in comparison with those of bronchoalveolar lavage and the Bal cathâ, and may be an acceptable method for diagnosing hospital-acquired pneumonia when no fiberoptic technique is available.
publisher Brazilian Society of Infectious Diseases
publishDate 2008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100015
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