Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001

This prospective study, involving 76 pregnant women infected with HIV, paired with their 79 exposed infants, was carried out between May 1996 and October 2001, at the Reference Department for Pregnant Women Infected with HIV in Campo Grande, Mato Grosso do Sul. The mean age of the pregnant women was 24 years; 88% (67/76) apparently were infected due to sexual practices; 88% (67/76) were housewives; 823% (63/76) graduated from junior high school; 14.5% (11/76) reported co-infection with Hepatitis C, 9.2% with Syphilis; 51% (39/76) learned the diagnosis during prenatal care; 67% (51/76) reported HIV clinical symptomatology and 9.2% (7/76) reported opportunistic infections. Elective cesareans were performed in 57% (43/76). The mean gestational age at delivery was 38 weeks and we found 12.5% (10/80) pronatis; 97% (74/76) had a ruptured membrane time after less than four hours and one child (1.3%) was nursed. ACTG 076 Protocol (AIDS Clinical Trial Group 076) was used in 80% (61/76) of the pregnant women, with 100% adherence; 62% (38/61) used zidovudine plus another antiretroviral in the gestation; 92% (73/79) of the infants used zidovudine after the birth and 19% (14/73) used zidovudine and lamivudine. The transmission rate in this study was 2.5%.

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Main Authors: Dal Fabbro,Márcia Maria Ferrairo Janini, Cunha,Rivaldo Venâncio da, Paniago,Anamaria Mello Miranda, Lindenberg,Andréa de Siqueira C., Freitas,Gisele Maria Brandão de, Nogueira,Susie Andries
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2005
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000100005
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spelling oai:scielo:S1413-867020050001000052005-06-06Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001Dal Fabbro,Márcia Maria Ferrairo JaniniCunha,Rivaldo Venâncio daPaniago,Anamaria Mello MirandaLindenberg,Andréa de Siqueira C.Freitas,Gisele Maria Brandão deNogueira,Susie Andries HIV/AIDS certical transmission prevention/prophylaxis Mato Grosso do Sul Brazil This prospective study, involving 76 pregnant women infected with HIV, paired with their 79 exposed infants, was carried out between May 1996 and October 2001, at the Reference Department for Pregnant Women Infected with HIV in Campo Grande, Mato Grosso do Sul. The mean age of the pregnant women was 24 years; 88% (67/76) apparently were infected due to sexual practices; 88% (67/76) were housewives; 823% (63/76) graduated from junior high school; 14.5% (11/76) reported co-infection with Hepatitis C, 9.2% with Syphilis; 51% (39/76) learned the diagnosis during prenatal care; 67% (51/76) reported HIV clinical symptomatology and 9.2% (7/76) reported opportunistic infections. Elective cesareans were performed in 57% (43/76). The mean gestational age at delivery was 38 weeks and we found 12.5% (10/80) pronatis; 97% (74/76) had a ruptured membrane time after less than four hours and one child (1.3%) was nursed. ACTG 076 Protocol (AIDS Clinical Trial Group 076) was used in 80% (61/76) of the pregnant women, with 100% adherence; 62% (38/61) used zidovudine plus another antiretroviral in the gestation; 92% (73/79) of the infants used zidovudine after the birth and 19% (14/73) used zidovudine and lamivudine. The transmission rate in this study was 2.5%.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.9 n.1 20052005-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000100005en10.1590/S1413-86702005000100005
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language English
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author Dal Fabbro,Márcia Maria Ferrairo Janini
Cunha,Rivaldo Venâncio da
Paniago,Anamaria Mello Miranda
Lindenberg,Andréa de Siqueira C.
Freitas,Gisele Maria Brandão de
Nogueira,Susie Andries
spellingShingle Dal Fabbro,Márcia Maria Ferrairo Janini
Cunha,Rivaldo Venâncio da
Paniago,Anamaria Mello Miranda
Lindenberg,Andréa de Siqueira C.
Freitas,Gisele Maria Brandão de
Nogueira,Susie Andries
Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
author_facet Dal Fabbro,Márcia Maria Ferrairo Janini
Cunha,Rivaldo Venâncio da
Paniago,Anamaria Mello Miranda
Lindenberg,Andréa de Siqueira C.
Freitas,Gisele Maria Brandão de
Nogueira,Susie Andries
author_sort Dal Fabbro,Márcia Maria Ferrairo Janini
title Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
title_short Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
title_full Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
title_fullStr Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
title_full_unstemmed Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001
title_sort prospective study on the prevention of vertical transmission of hiv in campo grande, mato grosso do sul, brazil, from 1996 to 2001
description This prospective study, involving 76 pregnant women infected with HIV, paired with their 79 exposed infants, was carried out between May 1996 and October 2001, at the Reference Department for Pregnant Women Infected with HIV in Campo Grande, Mato Grosso do Sul. The mean age of the pregnant women was 24 years; 88% (67/76) apparently were infected due to sexual practices; 88% (67/76) were housewives; 823% (63/76) graduated from junior high school; 14.5% (11/76) reported co-infection with Hepatitis C, 9.2% with Syphilis; 51% (39/76) learned the diagnosis during prenatal care; 67% (51/76) reported HIV clinical symptomatology and 9.2% (7/76) reported opportunistic infections. Elective cesareans were performed in 57% (43/76). The mean gestational age at delivery was 38 weeks and we found 12.5% (10/80) pronatis; 97% (74/76) had a ruptured membrane time after less than four hours and one child (1.3%) was nursed. ACTG 076 Protocol (AIDS Clinical Trial Group 076) was used in 80% (61/76) of the pregnant women, with 100% adherence; 62% (38/61) used zidovudine plus another antiretroviral in the gestation; 92% (73/79) of the infants used zidovudine after the birth and 19% (14/73) used zidovudine and lamivudine. The transmission rate in this study was 2.5%.
publisher Brazilian Society of Infectious Diseases
publishDate 2005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000100005
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