Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil

Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment.

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Main Authors: Rabahi,Marcelo Fouad, Rodrigues,Adriana Batista, Mello,Fernanda Queiroz de, Almeida Netto,Joaquim Caetano de, Kritski,Afrânio Lineu
Format: Digital revista
Language:English
Published: Brazilian Society of Infectious Diseases 2002
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200002
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spelling oai:scielo:S1413-867020020002000022003-03-25Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern BrazilRabahi,Marcelo FouadRodrigues,Adriana BatistaMello,Fernanda Queiroz deAlmeida Netto,Joaquim Caetano deKritski,Afrânio Lineu Tuberculosis treatment compliance TB control program Goiânia Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment.info:eu-repo/semantics/openAccessBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious Diseases v.6 n.2 20022002-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200002en10.1590/S1413-86702002000200002
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libraryname SciELO
language English
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author Rabahi,Marcelo Fouad
Rodrigues,Adriana Batista
Mello,Fernanda Queiroz de
Almeida Netto,Joaquim Caetano de
Kritski,Afrânio Lineu
spellingShingle Rabahi,Marcelo Fouad
Rodrigues,Adriana Batista
Mello,Fernanda Queiroz de
Almeida Netto,Joaquim Caetano de
Kritski,Afrânio Lineu
Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
author_facet Rabahi,Marcelo Fouad
Rodrigues,Adriana Batista
Mello,Fernanda Queiroz de
Almeida Netto,Joaquim Caetano de
Kritski,Afrânio Lineu
author_sort Rabahi,Marcelo Fouad
title Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
title_short Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
title_full Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
title_fullStr Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
title_full_unstemmed Noncompliance with tuberculosis treatment by patients at a tuberculosis and AIDS reference hospital in midwestern Brazil
title_sort noncompliance with tuberculosis treatment by patients at a tuberculosis and aids reference hospital in midwestern brazil
description Introduction: In developing countries, there is little information about the risk factors that predict noncompliance with tuberculosis (TB) treatment in hospitals. Objective: This study analyzes possible factors associated with noncompliance with TB treatment among patients treated at HAA. Design: A retrospective cohort study was made including all patients who initiated TB treatment at HAA, from January to December 1998. A standard form was used to review medical records and to collect data on each patient. This data was evaluated in comparison with data from the state TB control program. Results: Of the 341 patients included in the study, 186 (61.2%) were considered cured and 67 (22%) were non-compliant. The factors associated with noncompliance were: previous anti-TB treatment (RR = 1.95, 95% CI 1.29 to 2.93), prescription of drugs other than the standard first-line regimen proposed by the Brazilian Health Ministry (Rifampin + Isoniazide + Pyrazinamide) (RR = 0.54, 95% CI 0.35 to 0.83), the need for hospitalization (RR = 2.19, 95% CI 1.46 to 3.29) and non-inclusion in the hospital's TB Control Program for treatment follow up (RR = 0.54, 95% CI 0.35 to 0.82). Setting: Anuar Auad Hospital (HAA) - Goiânia, Goiás, Brazil. Conclusion: Our results indicate the importance of establishing Tuberculosis Control Programs in hospitals, while paying special attention to patients with risk factors for noncompliance with TB treatment.
publisher Brazilian Society of Infectious Diseases
publishDate 2002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200002
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