ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR

ABSTRACT Objective: To investigate the safety and efficacy of allogeneic platelet-rich plasma (PRP) in rotator cuff repair . Methods: Seventeen patients with a full-thickness rotator cuff tear were included. Ten patients underwent arthroscopic rotator cuff repair with allogeneic, and seven patients with autologous PRP. Three PRP gels in a volume 3 ml each were applied between the torn end and the greater tuberosity. Clinical outcomes were assessed preoperatively and at a minimum of 2 years after surgery. Structural outcomes were evaluated with the presence of retear and the change of the cross-sectional area (ACT) of the supraspinatus . Results: Allogeneic PRP did not cause any adverse events during the follow-up period. There was no significant difference in the clinical outcome measures between the two groups (all p > 0.05). The retear rate was 33.3% and 25.0% in the allogeneic group and autologous group, respectively (p = 0.764). The change between the one-year postoperative and immediately postoperative ACT was not also significantly different between the two groups (p = 0.373) . Conclusion: Allogeneic PRP in arthroscopic rotator cuff did not cause any local or general complications and that has the efficacy comparable to autologous PRP with respect to the clinical and structural outcomes. Level of Evidence III, Retrospective Comparative Study.

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Main Authors: JO,CHRIS HYUNCHUL, SHIN,JI SUN, LEE,SEUNG YEON, SHIN,SUE
Format: Digital revista
Language:English
Published: ATHA EDITORA 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522017000100038
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spelling oai:scielo:S1413-785220170001000382017-03-08ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIRJO,CHRIS HYUNCHULSHIN,JI SUNLEE,SEUNG YEONSHIN,SUE Platelet-rich plasma Rotator cuff Growth factors Tendon injuries ABSTRACT Objective: To investigate the safety and efficacy of allogeneic platelet-rich plasma (PRP) in rotator cuff repair . Methods: Seventeen patients with a full-thickness rotator cuff tear were included. Ten patients underwent arthroscopic rotator cuff repair with allogeneic, and seven patients with autologous PRP. Three PRP gels in a volume 3 ml each were applied between the torn end and the greater tuberosity. Clinical outcomes were assessed preoperatively and at a minimum of 2 years after surgery. Structural outcomes were evaluated with the presence of retear and the change of the cross-sectional area (ACT) of the supraspinatus . Results: Allogeneic PRP did not cause any adverse events during the follow-up period. There was no significant difference in the clinical outcome measures between the two groups (all p > 0.05). The retear rate was 33.3% and 25.0% in the allogeneic group and autologous group, respectively (p = 0.764). The change between the one-year postoperative and immediately postoperative ACT was not also significantly different between the two groups (p = 0.373) . Conclusion: Allogeneic PRP in arthroscopic rotator cuff did not cause any local or general complications and that has the efficacy comparable to autologous PRP with respect to the clinical and structural outcomes. Level of Evidence III, Retrospective Comparative Study.info:eu-repo/semantics/openAccessATHA EDITORAActa Ortopédica Brasileira v.25 n.1 20172017-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522017000100038en10.1590/1413-785220172501163417
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author JO,CHRIS HYUNCHUL
SHIN,JI SUN
LEE,SEUNG YEON
SHIN,SUE
spellingShingle JO,CHRIS HYUNCHUL
SHIN,JI SUN
LEE,SEUNG YEON
SHIN,SUE
ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
author_facet JO,CHRIS HYUNCHUL
SHIN,JI SUN
LEE,SEUNG YEON
SHIN,SUE
author_sort JO,CHRIS HYUNCHUL
title ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
title_short ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
title_full ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
title_fullStr ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
title_full_unstemmed ALLOGENEIC PLATELET-RICH PLASMA FOR ROTATOR CUFF REPAIR
title_sort allogeneic platelet-rich plasma for rotator cuff repair
description ABSTRACT Objective: To investigate the safety and efficacy of allogeneic platelet-rich plasma (PRP) in rotator cuff repair . Methods: Seventeen patients with a full-thickness rotator cuff tear were included. Ten patients underwent arthroscopic rotator cuff repair with allogeneic, and seven patients with autologous PRP. Three PRP gels in a volume 3 ml each were applied between the torn end and the greater tuberosity. Clinical outcomes were assessed preoperatively and at a minimum of 2 years after surgery. Structural outcomes were evaluated with the presence of retear and the change of the cross-sectional area (ACT) of the supraspinatus . Results: Allogeneic PRP did not cause any adverse events during the follow-up period. There was no significant difference in the clinical outcome measures between the two groups (all p > 0.05). The retear rate was 33.3% and 25.0% in the allogeneic group and autologous group, respectively (p = 0.764). The change between the one-year postoperative and immediately postoperative ACT was not also significantly different between the two groups (p = 0.373) . Conclusion: Allogeneic PRP in arthroscopic rotator cuff did not cause any local or general complications and that has the efficacy comparable to autologous PRP with respect to the clinical and structural outcomes. Level of Evidence III, Retrospective Comparative Study.
publisher ATHA EDITORA
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522017000100038
work_keys_str_mv AT jochrishyunchul allogeneicplateletrichplasmaforrotatorcuffrepair
AT shinjisun allogeneicplateletrichplasmaforrotatorcuffrepair
AT leeseungyeon allogeneicplateletrichplasmaforrotatorcuffrepair
AT shinsue allogeneicplateletrichplasmaforrotatorcuffrepair
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