Pediatric pulmonary embolism and nephrotic syndrome
Thromboembolic complications, such as pulmonary embolism, are well-documented complications in nephrotic syndrome. The authors report a case of a 10-year-old boy with nephrotic syndrome and history of thrombotic complications, who experienced a massive pulmonary embolism during nephrotic syndrome relapse. Clinical signs and symptoms were minimal; D-dimers were an important clue and computed tomography pulmonary angiography established the definitive diagnosis. Treatment with low weight heparin was effective. Screening for hereditary thrombophilia identified predisposition towards thrombosis. Although these events seem rare in children, the literature suggests that they are actually underdiagnosed. Clinicians should be aware of this clinical condition, in order to avoid delay or misdiagnosis and prevent a poor or fatal outcome.
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Sociedade Portuguesa de Nefrologia
2018
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oai:scielo:S0872-016920180002000082018-07-25Pediatric pulmonary embolism and nephrotic syndromeCosta,RaquelGomes,SusanaStone,RosárioFerreira,Rosário hypocoagulation nephrotic syndrome pediatrics pulmonary embolism Thromboembolic complications, such as pulmonary embolism, are well-documented complications in nephrotic syndrome. The authors report a case of a 10-year-old boy with nephrotic syndrome and history of thrombotic complications, who experienced a massive pulmonary embolism during nephrotic syndrome relapse. Clinical signs and symptoms were minimal; D-dimers were an important clue and computed tomography pulmonary angiography established the definitive diagnosis. Treatment with low weight heparin was effective. Screening for hereditary thrombophilia identified predisposition towards thrombosis. Although these events seem rare in children, the literature suggests that they are actually underdiagnosed. Clinicians should be aware of this clinical condition, in order to avoid delay or misdiagnosis and prevent a poor or fatal outcome.info:eu-repo/semantics/openAccessSociedade Portuguesa de NefrologiaPortuguese Journal of Nephrology & Hypertension v.32 n.2 20182018-06-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000200008en |
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Europa del Sur |
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English |
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Digital |
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Costa,Raquel Gomes,Susana Stone,Rosário Ferreira,Rosário |
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Costa,Raquel Gomes,Susana Stone,Rosário Ferreira,Rosário Pediatric pulmonary embolism and nephrotic syndrome |
| author_facet |
Costa,Raquel Gomes,Susana Stone,Rosário Ferreira,Rosário |
| author_sort |
Costa,Raquel |
| title |
Pediatric pulmonary embolism and nephrotic syndrome |
| title_short |
Pediatric pulmonary embolism and nephrotic syndrome |
| title_full |
Pediatric pulmonary embolism and nephrotic syndrome |
| title_fullStr |
Pediatric pulmonary embolism and nephrotic syndrome |
| title_full_unstemmed |
Pediatric pulmonary embolism and nephrotic syndrome |
| title_sort |
pediatric pulmonary embolism and nephrotic syndrome |
| description |
Thromboembolic complications, such as pulmonary embolism, are well-documented complications in nephrotic syndrome. The authors report a case of a 10-year-old boy with nephrotic syndrome and history of thrombotic complications, who experienced a massive pulmonary embolism during nephrotic syndrome relapse. Clinical signs and symptoms were minimal; D-dimers were an important clue and computed tomography pulmonary angiography established the definitive diagnosis. Treatment with low weight heparin was effective. Screening for hereditary thrombophilia identified predisposition towards thrombosis. Although these events seem rare in children, the literature suggests that they are actually underdiagnosed. Clinicians should be aware of this clinical condition, in order to avoid delay or misdiagnosis and prevent a poor or fatal outcome. |
| publisher |
Sociedade Portuguesa de Nefrologia |
| publishDate |
2018 |
| url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000200008 |
| work_keys_str_mv |
AT costaraquel pediatricpulmonaryembolismandnephroticsyndrome AT gomessusana pediatricpulmonaryembolismandnephroticsyndrome AT stonerosario pediatricpulmonaryembolismandnephroticsyndrome AT ferreirarosario pediatricpulmonaryembolismandnephroticsyndrome |
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1756001690976256000 |