RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW

RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW

Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules.

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Main Authors: Mohsin,Noor Ul Amin, Irfan,Muhammad
Format: Digital revista
Language:English
Published: Sociedad Chilena de Química 2018
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135
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spelling oai:scielo:S0717-970720180003041352018-10-03RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEWMohsin,Noor Ul AminIrfan,Muhammad Resveratrol (RSV) Wittig reaction aldol condensation natural molecules antitumor activity anti-Alzheimer activity Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules. info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.63 n.3 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135en10.4067/s0717-97072018000304135
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Mohsin,Noor Ul Amin
Irfan,Muhammad
spellingShingle Mohsin,Noor Ul Amin
Irfan,Muhammad
RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
author_facet Mohsin,Noor Ul Amin
Irfan,Muhammad
author_sort Mohsin,Noor Ul Amin
title RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_short RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_full RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_fullStr RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_full_unstemmed RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_sort recent approaches for the synthesis of hybrid resveratrol molecules and their biological activities: a review
description Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules.
publisher Sociedad Chilena de Química
publishDate 2018
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135
work_keys_str_mv AT mohsinnoorulamin recentapproachesforthesynthesisofhybridresveratrolmoleculesandtheirbiologicalactivitiesareview
AT irfanmuhammad recentapproachesforthesynthesisofhybridresveratrolmoleculesandtheirbiologicalactivitiesareview
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