SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE

SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE

Manganese(II) metal ion and sulfathiazole (Hstz) react with pyrrolidine (pyrro), piperidine (pipe) and ethylenediamine (en) to form the following mixed ligand complexes : [Mn(stz)2(pyrro)2], [Mn(stz)2(pipe)2] and [Mn(stz)2(en)2] which were characterized by physicochemical and spectroscopic methods. Their spectra indicated that the sulfathiazole is probably acting as amonoanionic unidentate chelating agent. The superoxide dismutase mimetic activity of the complexes was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.

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Main Authors: ANACONA,J.R, DIAZ,JESUS
Format: Digital revista
Language:English
Published: Sociedad Chilena de Química 2008
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000400014
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spelling oai:scielo:S0717-970720080004000142009-05-22SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLEANACONA,J.RDIAZ,JESUSManganese(II) metal ion and sulfathiazole (Hstz) react with pyrrolidine (pyrro), piperidine (pipe) and ethylenediamine (en) to form the following mixed ligand complexes : [Mn(stz)2(pyrro)2], [Mn(stz)2(pipe)2] and [Mn(stz)2(en)2] which were characterized by physicochemical and spectroscopic methods. Their spectra indicated that the sulfathiazole is probably acting as amonoanionic unidentate chelating agent. The superoxide dismutase mimetic activity of the complexes was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.53 n.4 20082008-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000400014en10.4067/S0717-97072008000400014
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
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region America del Sur
libraryname SciELO
language English
format Digital
author ANACONA,J.R
DIAZ,JESUS
spellingShingle ANACONA,J.R
DIAZ,JESUS
SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
author_facet ANACONA,J.R
DIAZ,JESUS
author_sort ANACONA,J.R
title SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
title_short SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
title_full SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
title_fullStr SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
title_full_unstemmed SYNTHESIS, CHARACTERIZATION AND SUPEROXIDE DISMUTASE ACTWITY OF THE MANGANESE(II) MIXED LIGAND COMPLEXES CONTAINING SULFATHIAZOLE
title_sort synthesis, characterization and superoxide dismutase actwity of the manganese(ii) mixed ligand complexes containing sulfathiazole
description Manganese(II) metal ion and sulfathiazole (Hstz) react with pyrrolidine (pyrro), piperidine (pipe) and ethylenediamine (en) to form the following mixed ligand complexes : [Mn(stz)2(pyrro)2], [Mn(stz)2(pipe)2] and [Mn(stz)2(en)2] which were characterized by physicochemical and spectroscopic methods. Their spectra indicated that the sulfathiazole is probably acting as amonoanionic unidentate chelating agent. The superoxide dismutase mimetic activity of the complexes was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.
publisher Sociedad Chilena de Química
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072008000400014
work_keys_str_mv AT anaconajr synthesischaracterizationandsuperoxidedismutaseactwityofthemanganeseiimixedligandcomplexescontainingsulfathiazole
AT diazjesus synthesischaracterizationandsuperoxidedismutaseactwityofthemanganeseiimixedligandcomplexescontainingsulfathiazole
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