SYNTHESIS OF 2-ARYL-1,3-PROPANEDIAMINES USING A ONE-POT KNOEVENAGEL-MICHAEL SEQUENCE
A simple synthetic route for the preparation of 2-phenyl-1,3-propanediamines, based on a Knoevenagel-Michael double condensation followed by reduction, was developed using nitromethane as reagent and solvent, and sodium bicarbonate as base in the first step, followed by catalytic hydrogenation over Adams catalyst
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| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Chilena de Química
2006
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000100006 |
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