Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients

Abstract HIV/syphilis co-infection is common because both conditions affect similar risk groups. HIV interferes with the natural history of syphilis, which often has atypical clinical features and nervous system involvement in the early stage of disease. We report the case of an HIV-positive patient with secondary syphilis, scaling palmoplantar keratoderma, scrotal eczema, balanitis and urethritis mimicking Reiter’s syndrome. Immunohistochemistry using polyclonal antibodies against Treponema pallidum revealed the presence of spirochetes, associated with the paretic form of parenchymal neurosyphilis. The patient was given crystalline penicillin, with complete resolution of dermatological and neurological symptoms, and no sequelae.

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Main Authors: Bastos,Thales Costa, Maia,Daniela Cristina Caetano, Gomes,Nathália Matos, Menezes,Carla Kellen da Silva, Francesconi,Valeska, Francesconi,Fabio
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700212
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spelling oai:scielo:S0365-059620150007002122015-11-19Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patientsBastos,Thales CostaMaia,Daniela Cristina CaetanoGomes,Nathália MatosMenezes,Carla Kellen da SilvaFrancesconi,ValeskaFrancesconi,Fabio Antibody-coated bacteria test, urinary HIV Nervous system diseases Neurosyphilis Syphilis Skin diseases, eczematous Treponema pallidum Abstract HIV/syphilis co-infection is common because both conditions affect similar risk groups. HIV interferes with the natural history of syphilis, which often has atypical clinical features and nervous system involvement in the early stage of disease. We report the case of an HIV-positive patient with secondary syphilis, scaling palmoplantar keratoderma, scrotal eczema, balanitis and urethritis mimicking Reiter’s syndrome. Immunohistochemistry using polyclonal antibodies against Treponema pallidum revealed the presence of spirochetes, associated with the paretic form of parenchymal neurosyphilis. The patient was given crystalline penicillin, with complete resolution of dermatological and neurological symptoms, and no sequelae.info:eu-repo/semantics/openAccessSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia v.90 n.3 suppl.1 20152015-06-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700212en10.1590/abd1806-4841.20153625
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countrycode BR
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libraryname SciELO
language English
format Digital
author Bastos,Thales Costa
Maia,Daniela Cristina Caetano
Gomes,Nathália Matos
Menezes,Carla Kellen da Silva
Francesconi,Valeska
Francesconi,Fabio
spellingShingle Bastos,Thales Costa
Maia,Daniela Cristina Caetano
Gomes,Nathália Matos
Menezes,Carla Kellen da Silva
Francesconi,Valeska
Francesconi,Fabio
Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
author_facet Bastos,Thales Costa
Maia,Daniela Cristina Caetano
Gomes,Nathália Matos
Menezes,Carla Kellen da Silva
Francesconi,Valeska
Francesconi,Fabio
author_sort Bastos,Thales Costa
title Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
title_short Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
title_full Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
title_fullStr Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
title_full_unstemmed Syphilis associated with paretic neurosyphilis mimicking Reiter’s syndrome in HIV-infected patients
title_sort syphilis associated with paretic neurosyphilis mimicking reiter’s syndrome in hiv-infected patients
description Abstract HIV/syphilis co-infection is common because both conditions affect similar risk groups. HIV interferes with the natural history of syphilis, which often has atypical clinical features and nervous system involvement in the early stage of disease. We report the case of an HIV-positive patient with secondary syphilis, scaling palmoplantar keratoderma, scrotal eczema, balanitis and urethritis mimicking Reiter’s syndrome. Immunohistochemistry using polyclonal antibodies against Treponema pallidum revealed the presence of spirochetes, associated with the paretic form of parenchymal neurosyphilis. The patient was given crystalline penicillin, with complete resolution of dermatological and neurological symptoms, and no sequelae.
publisher Sociedade Brasileira de Dermatologia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700212
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