Allogeneic hematopoietic stem cell transplantation in mycosis fungoides

Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of 2-4 years. The only curative option for mycosis fungoides may be hematopoietic allogeneic stem cell transplantation. We report the case of a patient with mycosis fungoides in an advanced stage (IIB), refractory to treatment options. She underwent allogeneic hematopoietic stem-cell transplantation (allo-HSCT). The patient remains in complete remission nineteen months after allo-HSCT. Allogeneic transplantation can alter the natural history of mycosis fungoides and should be considered in patients who have refractory disease or short-lived responses with standard therapies.

Bibliographic Details

Main Authors:	Atalla,Angelo, Hallack Neto,Abrahão Elias, Siqueira,Denise Bittencourt, Toledo,Gabriela Cumani
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Dermatologia 2013
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000800216
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