Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain)
Objective: To estimate the prevalence of hepatitis B virus (HBV) infection and vaccine-induced immunity in the region of Madrid, and to analyze their evolution over time. Methods: An observational, analytical, cross-sectional study was carried out in the population aged 16-80 years between 2008 and 2009. This was the last of four seroprevalence surveys in the region of Madrid. The prevalence of HBV infection and vaccine-induced immunity was estimated using multivariate logistic models and were compared with the prevalences in the 1989, 1993 and 1999 surveys. Results: In the population aged 16-80 years, the prevalence of HBV infection was 11.0% (95% CI: 9.8-12.3) and that of chronic infection was 0.7% (95% CI: 0.5-1.1). The prevalence of vaccine-induced immunity in the population aged 16-20 years was 73.0% (95% CI: 70.0-76.0). Compared with previous surveys, there was a decrease in the prevalence of HBV infection. Conclusions: Based on the prevalence of chronic infection (<1%), Madrid is a region with low HBV endemicity. Preventive strategies against HBV should especially target the immigrant population.
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Sociedad Española de Salud Pública y Administración Sanitaria (SESPAS)
2014
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oai:scielo:S0213-911120140006000102015-07-16Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain)Pedraza-Flechas,Ana MaríaGarcía-Comas,LuisOrdobás-Gavín,MaríaSanz-Moreno,Juan CarlosRamos-Blázquez,BelénAstray-Mochales,JenaroMoreno-Guillén,Santiago Hepatitis B Chronic hepatitis B Hepatitis B vaccine Seroepidemiologic Study Immunization Objective: To estimate the prevalence of hepatitis B virus (HBV) infection and vaccine-induced immunity in the region of Madrid, and to analyze their evolution over time. Methods: An observational, analytical, cross-sectional study was carried out in the population aged 16-80 years between 2008 and 2009. This was the last of four seroprevalence surveys in the region of Madrid. The prevalence of HBV infection and vaccine-induced immunity was estimated using multivariate logistic models and were compared with the prevalences in the 1989, 1993 and 1999 surveys. Results: In the population aged 16-80 years, the prevalence of HBV infection was 11.0% (95% CI: 9.8-12.3) and that of chronic infection was 0.7% (95% CI: 0.5-1.1). The prevalence of vaccine-induced immunity in the population aged 16-20 years was 73.0% (95% CI: 70.0-76.0). Compared with previous surveys, there was a decrease in the prevalence of HBV infection. Conclusions: Based on the prevalence of chronic infection (<1%), Madrid is a region with low HBV endemicity. Preventive strategies against HBV should especially target the immigrant population.Sociedad Española de Salud Pública y Administración Sanitaria (SESPAS)Gaceta Sanitaria v.28 n.6 20142014-12-01journal articletext/htmlhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0213-91112014000600010en |
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Pedraza-Flechas,Ana María García-Comas,Luis Ordobás-Gavín,María Sanz-Moreno,Juan Carlos Ramos-Blázquez,Belén Astray-Mochales,Jenaro Moreno-Guillén,Santiago |
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Pedraza-Flechas,Ana María García-Comas,Luis Ordobás-Gavín,María Sanz-Moreno,Juan Carlos Ramos-Blázquez,Belén Astray-Mochales,Jenaro Moreno-Guillén,Santiago Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
author_facet |
Pedraza-Flechas,Ana María García-Comas,Luis Ordobás-Gavín,María Sanz-Moreno,Juan Carlos Ramos-Blázquez,Belén Astray-Mochales,Jenaro Moreno-Guillén,Santiago |
author_sort |
Pedraza-Flechas,Ana María |
title |
Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
title_short |
Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
title_full |
Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
title_fullStr |
Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
title_full_unstemmed |
Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) |
title_sort |
hepatitis b virus infection and vaccine-induced immunity in madrid (spain) |
description |
Objective: To estimate the prevalence of hepatitis B virus (HBV) infection and vaccine-induced immunity in the region of Madrid, and to analyze their evolution over time. Methods: An observational, analytical, cross-sectional study was carried out in the population aged 16-80 years between 2008 and 2009. This was the last of four seroprevalence surveys in the region of Madrid. The prevalence of HBV infection and vaccine-induced immunity was estimated using multivariate logistic models and were compared with the prevalences in the 1989, 1993 and 1999 surveys. Results: In the population aged 16-80 years, the prevalence of HBV infection was 11.0% (95% CI: 9.8-12.3) and that of chronic infection was 0.7% (95% CI: 0.5-1.1). The prevalence of vaccine-induced immunity in the population aged 16-20 years was 73.0% (95% CI: 70.0-76.0). Compared with previous surveys, there was a decrease in the prevalence of HBV infection. Conclusions: Based on the prevalence of chronic infection (<1%), Madrid is a region with low HBV endemicity. Preventive strategies against HBV should especially target the immigrant population. |
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Sociedad Española de Salud Pública y Administración Sanitaria (SESPAS) |
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2014 |
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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0213-91112014000600010 |
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