Casein-derived peptides as an alternative ingredient for low-phenylalanine diets
Abstract Introduction: casein-derived peptides can be liberated both in vivo via normal digestion of casein, as well as in vitro via enzymatic hydrolysis. These peptides were suggested to have biological activity. Objectives: the aim of this study was to describe the production and characterization of casein peptides and to explore the potential of these peptides as an option for low-phenylalanine diets. Methods: peptides were produced by tryptic hydrolysis of sodium caseinate and acid precipitation with HCl, followed by precipitation with ethanol or aggregation of CaCl2 or ZnSO4. Results: the amino acid analysis revealed a significant reduction in the amount of phenylalanine from the original protein. Conclusion: casein-derived peptides could be a future alternative of short chain peptides to low-phenylalanine formulations.
Main Authors: | Krüger,Claudia C H, Azevedo,Thaise D, Piltz,Marina T, Silva,Ágatha T, Cândido,Lys M B |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Grupo Arán
2019
|
Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112019000300031 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Bioavailability and kinetics of the antihypertensive casein-derived peptide HLPLP in rats
by: Sánchez-Rivera, Laura, et al.
Published: (2014) -
Use of a casein-derived peptide and compositions thereof as antihypertensive
by: Recio, Isidra, et al.
Published: (2010-11-04) -
Resistance of casein-derived bioactive peptides to simulated gastrointestinal digestion
by: Contreras, María del Mar, et al.
Published: (2013) -
Implication of opioid receptors in the antihypertensive effect of a bovine casein hydrolysate and αs1-casein-derived peptides
by: Sánchez-Rivera, Laura, et al.
Published: (2020) -
Dairy Debaryomyces hansenii strains produce the antihypertensive casein-derived peptides LHLPLP and HLPLP
by: García Tejedor, Aurora, et al.
Published: (2014-12-11)