Use of therapeutic laser for prevention and treatment of oral mucositis
Oral mucositis (OM) affects patients who are submitted to hematopoietic stem cell transplantation (HSCT) due to high doses of chemotherapy and/or radiotherapy. The purpose of this investigation was to perform a comparative study of the frequency and evolution of OM among patients subjected to therapeutic laser and to the conventional therapy (use of mouthwash called "Mucositis Formula"). The patients were subjected to a myeloablative conditioning regimen before the allogeneic HSCT. Twenty-two patients were selected and divided into 2 groups: group I was irradiated with InGaAlP laser (660 nm) and GaAlAs laser (780 nm), 25 mW potency, 6.3J/cm² dose, in 10-s irradiation time, followed to conventional treatment; group II was subjected only to the conventional treatment. Both World Health Organization (WHO) scale and the Oral Mucositis Assessment Scale (OMAS) were used to evaluate the results. Data were analyzed by the non-parametric Wilcoxon test, with p<0.05 considered as statistically significant. Group I presented a lower frequency of OM (p=0.02) and lower mean scores, according to WHO and OMAS scales (p<0.01 and p=0.01, respectively). In conclusion, laser reduced the frequency and severity of OM, suggesting that therapeutic laser can be used both as a new form of prevention and treatment of OM.
Main Authors: | , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Fundação Odontológica de Ribeirão Preto
2009
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402009000300008 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0103-64402009000300008 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0103-644020090003000082009-09-21Use of therapeutic laser for prevention and treatment of oral mucositisKhouri,Vivian YoussefStracieri,Ana Beatriz Pereira LimaRodrigues,Maria CarolinaMoraes,Daniela Aparecida dePieroni,FabianoSimões,Belinda PintoVoltarelli,Júlio César oral mucositis chemotherapy radiotherapy allogeneic hematopoietic stem cell transplantation therapeutic laser Oral mucositis (OM) affects patients who are submitted to hematopoietic stem cell transplantation (HSCT) due to high doses of chemotherapy and/or radiotherapy. The purpose of this investigation was to perform a comparative study of the frequency and evolution of OM among patients subjected to therapeutic laser and to the conventional therapy (use of mouthwash called "Mucositis Formula"). The patients were subjected to a myeloablative conditioning regimen before the allogeneic HSCT. Twenty-two patients were selected and divided into 2 groups: group I was irradiated with InGaAlP laser (660 nm) and GaAlAs laser (780 nm), 25 mW potency, 6.3J/cm² dose, in 10-s irradiation time, followed to conventional treatment; group II was subjected only to the conventional treatment. Both World Health Organization (WHO) scale and the Oral Mucositis Assessment Scale (OMAS) were used to evaluate the results. Data were analyzed by the non-parametric Wilcoxon test, with p<0.05 considered as statistically significant. Group I presented a lower frequency of OM (p=0.02) and lower mean scores, according to WHO and OMAS scales (p<0.01 and p=0.01, respectively). In conclusion, laser reduced the frequency and severity of OM, suggesting that therapeutic laser can be used both as a new form of prevention and treatment of OM.info:eu-repo/semantics/openAccessFundação Odontológica de Ribeirão PretoBrazilian Dental Journal v.20 n.3 20092009-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402009000300008en10.1590/S0103-64402009000300008 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Khouri,Vivian Youssef Stracieri,Ana Beatriz Pereira Lima Rodrigues,Maria Carolina Moraes,Daniela Aparecida de Pieroni,Fabiano Simões,Belinda Pinto Voltarelli,Júlio César |
spellingShingle |
Khouri,Vivian Youssef Stracieri,Ana Beatriz Pereira Lima Rodrigues,Maria Carolina Moraes,Daniela Aparecida de Pieroni,Fabiano Simões,Belinda Pinto Voltarelli,Júlio César Use of therapeutic laser for prevention and treatment of oral mucositis |
author_facet |
Khouri,Vivian Youssef Stracieri,Ana Beatriz Pereira Lima Rodrigues,Maria Carolina Moraes,Daniela Aparecida de Pieroni,Fabiano Simões,Belinda Pinto Voltarelli,Júlio César |
author_sort |
Khouri,Vivian Youssef |
title |
Use of therapeutic laser for prevention and treatment of oral mucositis |
title_short |
Use of therapeutic laser for prevention and treatment of oral mucositis |
title_full |
Use of therapeutic laser for prevention and treatment of oral mucositis |
title_fullStr |
Use of therapeutic laser for prevention and treatment of oral mucositis |
title_full_unstemmed |
Use of therapeutic laser for prevention and treatment of oral mucositis |
title_sort |
use of therapeutic laser for prevention and treatment of oral mucositis |
description |
Oral mucositis (OM) affects patients who are submitted to hematopoietic stem cell transplantation (HSCT) due to high doses of chemotherapy and/or radiotherapy. The purpose of this investigation was to perform a comparative study of the frequency and evolution of OM among patients subjected to therapeutic laser and to the conventional therapy (use of mouthwash called "Mucositis Formula"). The patients were subjected to a myeloablative conditioning regimen before the allogeneic HSCT. Twenty-two patients were selected and divided into 2 groups: group I was irradiated with InGaAlP laser (660 nm) and GaAlAs laser (780 nm), 25 mW potency, 6.3J/cm² dose, in 10-s irradiation time, followed to conventional treatment; group II was subjected only to the conventional treatment. Both World Health Organization (WHO) scale and the Oral Mucositis Assessment Scale (OMAS) were used to evaluate the results. Data were analyzed by the non-parametric Wilcoxon test, with p<0.05 considered as statistically significant. Group I presented a lower frequency of OM (p=0.02) and lower mean scores, according to WHO and OMAS scales (p<0.01 and p=0.01, respectively). In conclusion, laser reduced the frequency and severity of OM, suggesting that therapeutic laser can be used both as a new form of prevention and treatment of OM. |
publisher |
Fundação Odontológica de Ribeirão Preto |
publishDate |
2009 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402009000300008 |
work_keys_str_mv |
AT khourivivianyoussef useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT stracierianabeatrizpereiralima useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT rodriguesmariacarolina useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT moraesdanielaaparecidade useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT pieronifabiano useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT simoesbelindapinto useoftherapeuticlaserforpreventionandtreatmentoforalmucositis AT voltarellijuliocesar useoftherapeuticlaserforpreventionandtreatmentoforalmucositis |
_version_ |
1756404475265810432 |