Skeletal muscle ischemia and reperfusion in rats increase lipid peroxidation in rats

PURPOSE: To determine the effects of 30 minutes of ischemia followed by 30 minutes of reperfusion in skeletal muscle of rats receiving three different diets (supplemented, normal and vitamin E deficient) on lipoperoxidation (LP). METHODS: LP measured by TBARS levels, and plasma and hepatic concentrations of vitamin E measured by HPLC. RESULTS: The deficient group presented higher lipoperoxidation levels in muscle compared to the control and supplemented groups. CONCLUSION: Supplementation with vitamin E decrease the free radicals production in ischemia/reperfusion in skeletal muscle of rats.

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Bibliographic Details
Main Authors: Piccinato,Carlos Eli, De Domenico Jr,Armando, Jordão Jr,Alceu Afonso, Vannucchi,Helio
Format: Digital revista
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2004
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502004000500018
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