Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure

Abstract Introduction: The number of kidney transplants (KTx) is increasing in Brazil and, consequently, the costs of this procedure increase the country's health budget. We retrospectively evaluated the data of kidney transplant procedures until hospital discharge, according to kidney function recovery after the procedure. Methods: Retrospective analysis of the non-sensitized, 1st KTx from deceased donors performed between Jan/2010 to Dec/2017. Results: Out of the 1300 KTx from deceased donors performed in this period, 730 patients were studied and divided into 3 groups: Immediate Renal Function (IRF) - decrease in serum creatinine ≥ 10% on two consecutive days; Delayed Graft Function (DGF) - decrease in serum creatinine <10% on two consecutive days, without the need for dialysis, and Dialysis (D) - need for dialysis during the first week. Patients in group D stayed longer in the hospital compared to DGF and IRF (21, 11 and 8 days respectively, p < 0.001). More D patients (21%) were admitted to the ICU and performed a greater number of laboratory tests (p < 0.001) and renal biopsies (p < 0.001), in addition to receiving a higher amount of immunosuppressants. Total hospital costs were higher in group D and DGF compared to IRF (U$ 7.021,48; U$ 3.603,42 and U$ 2.642,37 respectively, p < 0.001). Conclusion: The costs of the transplant procedure is impacted by the recovery of kidney function after the transplant. The reimbursement for each of these different kidney function outcomes should be individualized in order to cover their real costs.

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Auteurs principaux: Quinino,Raquel Martins e, Agena,Fabiana, Paula,Flávio Jota de, Nahas,William Carlos, David-Neto,Elias
Format: Digital revista
Langue:English
Publié: Sociedade Brasileira de Nefrologia 2021
Accès en ligne:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300375
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spelling oai:scielo:S0101-280020210003003752021-11-05Comparative analysis of kidney transplant costs related to recovery of renal function after the procedureQuinino,Raquel Martins eAgena,FabianaPaula,Flávio Jota deNahas,William CarlosDavid-Neto,Elias Kidney Transplantation Delayed Graft Function Economics, Pharmaceutical Abstract Introduction: The number of kidney transplants (KTx) is increasing in Brazil and, consequently, the costs of this procedure increase the country's health budget. We retrospectively evaluated the data of kidney transplant procedures until hospital discharge, according to kidney function recovery after the procedure. Methods: Retrospective analysis of the non-sensitized, 1st KTx from deceased donors performed between Jan/2010 to Dec/2017. Results: Out of the 1300 KTx from deceased donors performed in this period, 730 patients were studied and divided into 3 groups: Immediate Renal Function (IRF) - decrease in serum creatinine ≥ 10% on two consecutive days; Delayed Graft Function (DGF) - decrease in serum creatinine <10% on two consecutive days, without the need for dialysis, and Dialysis (D) - need for dialysis during the first week. Patients in group D stayed longer in the hospital compared to DGF and IRF (21, 11 and 8 days respectively, p < 0.001). More D patients (21%) were admitted to the ICU and performed a greater number of laboratory tests (p < 0.001) and renal biopsies (p < 0.001), in addition to receiving a higher amount of immunosuppressants. Total hospital costs were higher in group D and DGF compared to IRF (U$ 7.021,48; U$ 3.603,42 and U$ 2.642,37 respectively, p < 0.001). Conclusion: The costs of the transplant procedure is impacted by the recovery of kidney function after the transplant. The reimbursement for each of these different kidney function outcomes should be individualized in order to cover their real costs.info:eu-repo/semantics/openAccessSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology v.43 n.3 20212021-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300375en10.1590/2175-8239-jbn-2020-0172
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country Brasil
countrycode BR
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libraryname SciELO
language English
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author Quinino,Raquel Martins e
Agena,Fabiana
Paula,Flávio Jota de
Nahas,William Carlos
David-Neto,Elias
spellingShingle Quinino,Raquel Martins e
Agena,Fabiana
Paula,Flávio Jota de
Nahas,William Carlos
David-Neto,Elias
Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
author_facet Quinino,Raquel Martins e
Agena,Fabiana
Paula,Flávio Jota de
Nahas,William Carlos
David-Neto,Elias
author_sort Quinino,Raquel Martins e
title Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
title_short Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
title_full Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
title_fullStr Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
title_full_unstemmed Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
title_sort comparative analysis of kidney transplant costs related to recovery of renal function after the procedure
description Abstract Introduction: The number of kidney transplants (KTx) is increasing in Brazil and, consequently, the costs of this procedure increase the country's health budget. We retrospectively evaluated the data of kidney transplant procedures until hospital discharge, according to kidney function recovery after the procedure. Methods: Retrospective analysis of the non-sensitized, 1st KTx from deceased donors performed between Jan/2010 to Dec/2017. Results: Out of the 1300 KTx from deceased donors performed in this period, 730 patients were studied and divided into 3 groups: Immediate Renal Function (IRF) - decrease in serum creatinine ≥ 10% on two consecutive days; Delayed Graft Function (DGF) - decrease in serum creatinine <10% on two consecutive days, without the need for dialysis, and Dialysis (D) - need for dialysis during the first week. Patients in group D stayed longer in the hospital compared to DGF and IRF (21, 11 and 8 days respectively, p < 0.001). More D patients (21%) were admitted to the ICU and performed a greater number of laboratory tests (p < 0.001) and renal biopsies (p < 0.001), in addition to receiving a higher amount of immunosuppressants. Total hospital costs were higher in group D and DGF compared to IRF (U$ 7.021,48; U$ 3.603,42 and U$ 2.642,37 respectively, p < 0.001). Conclusion: The costs of the transplant procedure is impacted by the recovery of kidney function after the transplant. The reimbursement for each of these different kidney function outcomes should be individualized in order to cover their real costs.
publisher Sociedade Brasileira de Nefrologia
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300375
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