Granulomatous intersticial nephritis secondary to sarcoidosis
ABSTRACT Introduction: Granulomatous interstitial nephritis is a rare condition, in which renal involvement is uncommon. Its etiology is variable, and may be medicinal, infectious or inflammatory origin. Case report: This is a 65-year-old male patient with renal lesions of unknown etiology, associated with hypercalcaemia. During the investigation, cardiac insufficiency with diastolic dysfunction and interstitial lung involvement on chest tomography were evidenced. Renal function (glomerular filtration rate) has partially improved with clinical measures. Renal biopsy was performed, which showed moderate interstitial lesion with tuberculoid granulomas without caseous necrosis. Conclusion: The objective of the article was to describe a case of NIG and to alert to the importance of its clinical investigation. In this case, renal biopsy, associated with systemic clinical manifestations, contributed to the diagnosis of sarcoidosis.
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Sociedade Brasileira de Nefrologia
2017
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oai:scielo:S0101-280020170004004732018-01-04Granulomatous intersticial nephritis secondary to sarcoidosisPiraciaba,Tamires TeixeiraBalda,Carlos AlbertoMoura,Luiz Antônio Ribeiro dePereira,Carlos Alberto de CastroKirsztajn,Gianna Mastroianni hypercalcemia interstitial nephritis sarcoidosis ABSTRACT Introduction: Granulomatous interstitial nephritis is a rare condition, in which renal involvement is uncommon. Its etiology is variable, and may be medicinal, infectious or inflammatory origin. Case report: This is a 65-year-old male patient with renal lesions of unknown etiology, associated with hypercalcaemia. During the investigation, cardiac insufficiency with diastolic dysfunction and interstitial lung involvement on chest tomography were evidenced. Renal function (glomerular filtration rate) has partially improved with clinical measures. Renal biopsy was performed, which showed moderate interstitial lesion with tuberculoid granulomas without caseous necrosis. Conclusion: The objective of the article was to describe a case of NIG and to alert to the importance of its clinical investigation. In this case, renal biopsy, associated with systemic clinical manifestations, contributed to the diagnosis of sarcoidosis.info:eu-repo/semantics/openAccessSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology v.39 n.4 20172017-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000400473en10.5935/0101-2800.20170084 |
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Brasil |
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BR |
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revista |
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America del Sur |
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| language |
English |
| format |
Digital |
| author |
Piraciaba,Tamires Teixeira Balda,Carlos Alberto Moura,Luiz Antônio Ribeiro de Pereira,Carlos Alberto de Castro Kirsztajn,Gianna Mastroianni |
| spellingShingle |
Piraciaba,Tamires Teixeira Balda,Carlos Alberto Moura,Luiz Antônio Ribeiro de Pereira,Carlos Alberto de Castro Kirsztajn,Gianna Mastroianni Granulomatous intersticial nephritis secondary to sarcoidosis |
| author_facet |
Piraciaba,Tamires Teixeira Balda,Carlos Alberto Moura,Luiz Antônio Ribeiro de Pereira,Carlos Alberto de Castro Kirsztajn,Gianna Mastroianni |
| author_sort |
Piraciaba,Tamires Teixeira |
| title |
Granulomatous intersticial nephritis secondary to sarcoidosis |
| title_short |
Granulomatous intersticial nephritis secondary to sarcoidosis |
| title_full |
Granulomatous intersticial nephritis secondary to sarcoidosis |
| title_fullStr |
Granulomatous intersticial nephritis secondary to sarcoidosis |
| title_full_unstemmed |
Granulomatous intersticial nephritis secondary to sarcoidosis |
| title_sort |
granulomatous intersticial nephritis secondary to sarcoidosis |
| description |
ABSTRACT Introduction: Granulomatous interstitial nephritis is a rare condition, in which renal involvement is uncommon. Its etiology is variable, and may be medicinal, infectious or inflammatory origin. Case report: This is a 65-year-old male patient with renal lesions of unknown etiology, associated with hypercalcaemia. During the investigation, cardiac insufficiency with diastolic dysfunction and interstitial lung involvement on chest tomography were evidenced. Renal function (glomerular filtration rate) has partially improved with clinical measures. Renal biopsy was performed, which showed moderate interstitial lesion with tuberculoid granulomas without caseous necrosis. Conclusion: The objective of the article was to describe a case of NIG and to alert to the importance of its clinical investigation. In this case, renal biopsy, associated with systemic clinical manifestations, contributed to the diagnosis of sarcoidosis. |
| publisher |
Sociedade Brasileira de Nefrologia |
| publishDate |
2017 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000400473 |
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| _version_ |
1756392645385519104 |