Retina assessment by optical coherence tomography of diabetic dogs
ABSTRACT: Diabetes mellitus is one of the most common endocrine disorders characterized by relative or absolute lack of insulin; this can lead to several ocular manifestations, among them diabetic retinopathy and cataracts. Diabetic retinopathy (DR) is a microangiopathy that involves retinal precapillary arterioles, postcapillary venules, and large vessels, causing them to be functionally and anatomically incompetent. Hyperglycemia seems to be the most probable cause of damage to the retina due to interference in cellular metabolism and transduction processes. The aim of this study was to evaluate retinal thickness in eight diabetic dogs, four females and four males of different breeds and ages ranging from 6 to 15 years, by optical coherence tomography (OCT) and to compare them with non-diabetic dogs. Assessment provided by OCT in diabetic dogs showed retinal layers thinning and loss of stratification when compared to non-diabetic dogs (198μm versus 219μm respectively), with statistical significance (p=0.008). OCT images may suggest that diabetes mellitus causes retinal neuropathy in dogs, as also seen in diabetic humans.
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Digital revista |
| Idioma: | English |
| Publicado: |
Colégio Brasileiro de Patologia Animal - CBPA
2018
|
| Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018001001966 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0100-736X2018001001966 |
|---|---|
| record_format |
ojs |
| spelling |
oai:scielo:S0100-736X20180010019662018-11-26Retina assessment by optical coherence tomography of diabetic dogsBraga-Sá,Michelle B.P.Barros,Paulo S.M.Jorge,Juliana S.Dongo,PamelaFinkensieper,PaulaBolzan,Aline A.Watanabe,Sung S.Safatle,Angélica M.V. Optical coherence tomography OCT retina dogs retinal detachment retinal atrophy clinics ABSTRACT: Diabetes mellitus is one of the most common endocrine disorders characterized by relative or absolute lack of insulin; this can lead to several ocular manifestations, among them diabetic retinopathy and cataracts. Diabetic retinopathy (DR) is a microangiopathy that involves retinal precapillary arterioles, postcapillary venules, and large vessels, causing them to be functionally and anatomically incompetent. Hyperglycemia seems to be the most probable cause of damage to the retina due to interference in cellular metabolism and transduction processes. The aim of this study was to evaluate retinal thickness in eight diabetic dogs, four females and four males of different breeds and ages ranging from 6 to 15 years, by optical coherence tomography (OCT) and to compare them with non-diabetic dogs. Assessment provided by OCT in diabetic dogs showed retinal layers thinning and loss of stratification when compared to non-diabetic dogs (198μm versus 219μm respectively), with statistical significance (p=0.008). OCT images may suggest that diabetes mellitus causes retinal neuropathy in dogs, as also seen in diabetic humans.info:eu-repo/semantics/openAccessColégio Brasileiro de Patologia Animal - CBPAPesquisa Veterinária Brasileira v.38 n.10 20182018-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018001001966en10.1590/1678-5150-pvb-5614 |
| institution |
SCIELO |
| collection |
OJS |
| country |
Brasil |
| countrycode |
BR |
| component |
Revista |
| access |
En linea |
| databasecode |
rev-scielo-br |
| tag |
revista |
| region |
America del Sur |
| libraryname |
SciELO |
| language |
English |
| format |
Digital |
| author |
Braga-Sá,Michelle B.P. Barros,Paulo S.M. Jorge,Juliana S. Dongo,Pamela Finkensieper,Paula Bolzan,Aline A. Watanabe,Sung S. Safatle,Angélica M.V. |
| spellingShingle |
Braga-Sá,Michelle B.P. Barros,Paulo S.M. Jorge,Juliana S. Dongo,Pamela Finkensieper,Paula Bolzan,Aline A. Watanabe,Sung S. Safatle,Angélica M.V. Retina assessment by optical coherence tomography of diabetic dogs |
| author_facet |
Braga-Sá,Michelle B.P. Barros,Paulo S.M. Jorge,Juliana S. Dongo,Pamela Finkensieper,Paula Bolzan,Aline A. Watanabe,Sung S. Safatle,Angélica M.V. |
| author_sort |
Braga-Sá,Michelle B.P. |
| title |
Retina assessment by optical coherence tomography of diabetic dogs |
| title_short |
Retina assessment by optical coherence tomography of diabetic dogs |
| title_full |
Retina assessment by optical coherence tomography of diabetic dogs |
| title_fullStr |
Retina assessment by optical coherence tomography of diabetic dogs |
| title_full_unstemmed |
Retina assessment by optical coherence tomography of diabetic dogs |
| title_sort |
retina assessment by optical coherence tomography of diabetic dogs |
| description |
ABSTRACT: Diabetes mellitus is one of the most common endocrine disorders characterized by relative or absolute lack of insulin; this can lead to several ocular manifestations, among them diabetic retinopathy and cataracts. Diabetic retinopathy (DR) is a microangiopathy that involves retinal precapillary arterioles, postcapillary venules, and large vessels, causing them to be functionally and anatomically incompetent. Hyperglycemia seems to be the most probable cause of damage to the retina due to interference in cellular metabolism and transduction processes. The aim of this study was to evaluate retinal thickness in eight diabetic dogs, four females and four males of different breeds and ages ranging from 6 to 15 years, by optical coherence tomography (OCT) and to compare them with non-diabetic dogs. Assessment provided by OCT in diabetic dogs showed retinal layers thinning and loss of stratification when compared to non-diabetic dogs (198μm versus 219μm respectively), with statistical significance (p=0.008). OCT images may suggest that diabetes mellitus causes retinal neuropathy in dogs, as also seen in diabetic humans. |
| publisher |
Colégio Brasileiro de Patologia Animal - CBPA |
| publishDate |
2018 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2018001001966 |
| work_keys_str_mv |
AT bragasamichellebp retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT barrospaulosm retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT jorgejulianas retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT dongopamela retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT finkensieperpaula retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT bolzanalinea retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT watanabesungs retinaassessmentbyopticalcoherencetomographyofdiabeticdogs AT safatleangelicamv retinaassessmentbyopticalcoherencetomographyofdiabeticdogs |
| _version_ |
1756390241937129472 |