Thermodynamic study of the solubility of triclocarban in ethanol + propylene glycol mixtures
By using the van't Hoff and Gibbs equations the apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution for triclocarban in ethanol + propylene glycol mixtures were evaluated from solubility data determined at temperatures from (293.15 to 313.15) K. The drug solubility was greatest in the mixture with 0.60 in mass fraction of ethanol and lowest in neat propylene glycol at almost all the temperatures studied. Non-linear enthalpy-entropy compensation is found indicating apparently different mechanisms of the solution process according to the mixtures composition.
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Digital revista |
| Idioma: | English |
| Publicado: |
Sociedade Brasileira de Química
2012
|
| Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000200009 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
