Diagnosis of Schistosoma mansoni infections: what are the choices in Brazilian low-endemic areas?

The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the diagnostic method recommended by the World Health Organization (WHO) to assess these infections, but this method is not sensitive enough in the context of low egg excretion. In this regard, potential alternatives are being employed to overcome the limits of the Kato-Katz technique. In the present review, we evaluated the performance of parasitological and immunological approaches adopted in Brazilian areas. Currently, the diagnostic choices involve a combination of strategies, including the utilisation of antibody methods to screen individuals and then subsequent confirmation of positive cases by intensive parasitological investigations.

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Autores principales: Silva-Moraes,Vanessa, Shollenberger,Lisa M, Siqueira,Liliane Maria Vidal, Castro-Borges,William, Harn,Donald A, Grenfell,Rafaella Fortini Queiroz e, Rabello,Ana Lucia Teles, Coelho,Paulo Marcos Zech
Formato: Digital revista
Idioma:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100200
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