Acute schistosomiasis mansoni: revisited and reconsidered

Acute schistosomiasis mansoni: revisited and reconsidered

Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver abscesses, brain tumours and myeloradiculopathy. Hypereosinophilia is common and aids diagnosis. The disease has been overlooked, misdiagnosed, underestimated and underreported in endemic areas, but risk groups are well known, including military recruits, some religious congregations, rural tourists and people practicing recreational water sports. Serology may help in diagnosis, but the finding of necrotic-exudative granulomata in a liver biopsy specimen is pathognomonic. Differentials include malaria, tuberculosis, typhoid fever, kala-azar, prolonged Salmonella bacteraemia, lymphoma, toxocariasis, liver abscesses and fever of undetermined origin. For symptomatic hospitalised patients, treatment with steroids and schistosomicides is recommended. Treatment is curative in those timely diagnosed.

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Main Author: Lambertucci,José Roberto
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000400012
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spelling oai:scielo:S0074-027620100004000122010-08-06Acute schistosomiasis mansoni: revisited and reconsideredLambertucci,José Roberto acute schistosomiasis cercarial dermatitis FUO dermatitis neuroschistosomiasis pyogenic liver abscesses Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver abscesses, brain tumours and myeloradiculopathy. Hypereosinophilia is common and aids diagnosis. The disease has been overlooked, misdiagnosed, underestimated and underreported in endemic areas, but risk groups are well known, including military recruits, some religious congregations, rural tourists and people practicing recreational water sports. Serology may help in diagnosis, but the finding of necrotic-exudative granulomata in a liver biopsy specimen is pathognomonic. Differentials include malaria, tuberculosis, typhoid fever, kala-azar, prolonged Salmonella bacteraemia, lymphoma, toxocariasis, liver abscesses and fever of undetermined origin. For symptomatic hospitalised patients, treatment with steroids and schistosomicides is recommended. Treatment is curative in those timely diagnosed.info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.105 n.4 20102010-07-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000400012en10.1590/S0074-02762010000400012
institution SCIELO
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country Brasil
countrycode BR
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access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Lambertucci,José Roberto
spellingShingle Lambertucci,José Roberto
Acute schistosomiasis mansoni: revisited and reconsidered
author_facet Lambertucci,José Roberto
author_sort Lambertucci,José Roberto
title Acute schistosomiasis mansoni: revisited and reconsidered
title_short Acute schistosomiasis mansoni: revisited and reconsidered
title_full Acute schistosomiasis mansoni: revisited and reconsidered
title_fullStr Acute schistosomiasis mansoni: revisited and reconsidered
title_full_unstemmed Acute schistosomiasis mansoni: revisited and reconsidered
title_sort acute schistosomiasis mansoni: revisited and reconsidered
description Acute schistosomiasis is a systemic hypersensitivity reaction against the migrating schistosomula and eggs. A variety of clinical manifestations appear during the migration of schistosomes in humans: cercarial dermatitis, fever, pneumonia, diarrhoea, hepatomegaly, splenomegaly, skin lesions, liver abscesses, brain tumours and myeloradiculopathy. Hypereosinophilia is common and aids diagnosis. The disease has been overlooked, misdiagnosed, underestimated and underreported in endemic areas, but risk groups are well known, including military recruits, some religious congregations, rural tourists and people practicing recreational water sports. Serology may help in diagnosis, but the finding of necrotic-exudative granulomata in a liver biopsy specimen is pathognomonic. Differentials include malaria, tuberculosis, typhoid fever, kala-azar, prolonged Salmonella bacteraemia, lymphoma, toxocariasis, liver abscesses and fever of undetermined origin. For symptomatic hospitalised patients, treatment with steroids and schistosomicides is recommended. Treatment is curative in those timely diagnosed.
publisher Instituto Oswaldo Cruz, Ministério da Saúde
publishDate 2010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000400012
work_keys_str_mv AT lambertuccijoseroberto acuteschistosomiasismansonirevisitedandreconsidered
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