Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil
This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.
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Instituto Oswaldo Cruz, Ministério da Saúde
2002
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oai:scielo:S0074-027620020006000052002-10-16Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, BrazilSilva-Vergara,Mario LeónCosta Júnior,José CarlosBarata,Cristina HuebCuri,Vítor Guilherme MalufTiveron Júnior,Carlos GiovanniTeixeira,Alan César hantavirus hantavirus pulmonary syndrome/HPS Sin Nombre virus Minas Gerais Brazil This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.97 n.6 20022002-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600005en10.1590/S0074-02762002000600005 |
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| author |
Silva-Vergara,Mario León Costa Júnior,José Carlos Barata,Cristina Hueb Curi,Vítor Guilherme Maluf Tiveron Júnior,Carlos Giovanni Teixeira,Alan César |
| spellingShingle |
Silva-Vergara,Mario León Costa Júnior,José Carlos Barata,Cristina Hueb Curi,Vítor Guilherme Maluf Tiveron Júnior,Carlos Giovanni Teixeira,Alan César Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| author_facet |
Silva-Vergara,Mario León Costa Júnior,José Carlos Barata,Cristina Hueb Curi,Vítor Guilherme Maluf Tiveron Júnior,Carlos Giovanni Teixeira,Alan César |
| author_sort |
Silva-Vergara,Mario León |
| title |
Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| title_short |
Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| title_full |
Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| title_fullStr |
Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| title_full_unstemmed |
Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil |
| title_sort |
hantavirus pulmonary syndrome in uberaba, minas gerais, brazil |
| description |
This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS. |
| publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
| publishDate |
2002 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600005 |
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