A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis

A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.

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Main Authors: Valda Rodriguez,Luis, Dedet,Jean-Pierre, Paredtes,Virginia, Mendoza,Carmelo, Cardenas,Fernando
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1995
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020
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spelling oai:scielo:S0074-027619950004000202009-06-01A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasisValda Rodriguez,LuisDedet,Jean-PierreParedtes,VirginiaMendoza,CarmeloCardenas,Fernando mucocutaneous leishmaniasis treatmetn amphotericin B itraconazole A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected. info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.90 n.4 19951995-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020en10.1590/S0074-02761995000400020
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countrycode BR
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access En linea
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region America del Sur
libraryname SciELO
language English
format Digital
author Valda Rodriguez,Luis
Dedet,Jean-Pierre
Paredtes,Virginia
Mendoza,Carmelo
Cardenas,Fernando
spellingShingle Valda Rodriguez,Luis
Dedet,Jean-Pierre
Paredtes,Virginia
Mendoza,Carmelo
Cardenas,Fernando
A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
author_facet Valda Rodriguez,Luis
Dedet,Jean-Pierre
Paredtes,Virginia
Mendoza,Carmelo
Cardenas,Fernando
author_sort Valda Rodriguez,Luis
title A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_short A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_full A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_fullStr A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_full_unstemmed A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_sort randomized trial of amphotericin b alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
description A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.
publisher Instituto Oswaldo Cruz, Ministério da Saúde
publishDate 1995
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020
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