The significance of variation in the susceptibility of Schistosoma mansoni to the antischistosomal drug oxamniquine
Clinical and laboratory evidence is reviewed which shows that there is a great deal of variation in the susceptibility of Schistosoma mansoni to oxamniquine. This variation occurs both among endemic regions and within endemic regions in Brazil and Kenya. It is genetically controlled. It is suggested that the parasite possesses a large capacity for developing resistance to the drug and that resistance will develop where sufficient drug pressure is maintained.
Saved in:
Main Author: | Kinoti,G. K. |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
1987
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800026 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Stability of Schistosoma mansoni progeny to antischistosomal drugs
by: Dias,Luiz Candido de Souza, et al.
Published: (1985) -
Response of drug resistant isolates of Schistosoma mansoni to antischistosomal agents
by: Drescher,Kristen M., et al.
Published: (1993) -
Schistogram changes after administration of antischistosomal drugs in mice at the early phase of Schistosoma mansoni infection
by: Vimieiro,Andréa Cássia Simões, et al.
Published: (2013) -
Schistosoma mansoni: structural damage after treatment with oxamniquine
by: Magalhães Filho,Ageu, et al.
Published: (1987) -
Altered Response of Strain of Schistosoma mansoni to Oxamniquine and Praziquantel
by: Bonesso-Sabadini,Patrícia Ivana Pires, et al.
Published: (2002)