Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients

Abstract INTRODUCTION Solid-organ transplant recipients are at risk of hepatitis E virus (HEV) infection. We analyzed the seroprevalence/risk factors of HEV in Croatian liver transplant recipients. METHODS Two hundred forty-two serum samples were tested for HEV immunoglobuline IgG/IgM and HEV RNA. Sociodemographic data and risk factors were collected using a questionnaire. RESULTS HEV IgG seroprevalence rate was 24.4%. Positive/equivocal HEV IgM were found in two patients. HEV RNA was not detected. Logistic regression showed that older age, female gender, rural area/farm, water well, and septic tank were associated with HEV seropositivity. CONCLUSIONS This study revealed a high exposure rate to HEV in Croatian liver recipients.

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Main Authors: Mrzljak,Anna, Dinjar-Kujundzic,Petra, Vilibic-Cavlek,Tatjana, Jemersic,Lorena, Prpic,Jelena, Dakovic-Rode,Oktavija, Kolaric,Branko, Vince,Adriana
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100690
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spelling oai:scielo:S0037-868220190001006902019-10-07Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipientsMrzljak,AnnaDinjar-Kujundzic,PetraVilibic-Cavlek,TatjanaJemersic,LorenaPrpic,JelenaDakovic-Rode,OktavijaKolaric,BrankoVince,Adriana Hepatitis E vírus Seroprevalence Risk factors Liver transplant recipientes Croatia Abstract INTRODUCTION Solid-organ transplant recipients are at risk of hepatitis E virus (HEV) infection. We analyzed the seroprevalence/risk factors of HEV in Croatian liver transplant recipients. METHODS Two hundred forty-two serum samples were tested for HEV immunoglobuline IgG/IgM and HEV RNA. Sociodemographic data and risk factors were collected using a questionnaire. RESULTS HEV IgG seroprevalence rate was 24.4%. Positive/equivocal HEV IgM were found in two patients. HEV RNA was not detected. Logistic regression showed that older age, female gender, rural area/farm, water well, and septic tank were associated with HEV seropositivity. CONCLUSIONS This study revealed a high exposure rate to HEV in Croatian liver recipients.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.52 20192019-01-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100690en10.1590/0037-8682-0302-2019
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countrycode BR
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region America del Sur
libraryname SciELO
language English
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author Mrzljak,Anna
Dinjar-Kujundzic,Petra
Vilibic-Cavlek,Tatjana
Jemersic,Lorena
Prpic,Jelena
Dakovic-Rode,Oktavija
Kolaric,Branko
Vince,Adriana
spellingShingle Mrzljak,Anna
Dinjar-Kujundzic,Petra
Vilibic-Cavlek,Tatjana
Jemersic,Lorena
Prpic,Jelena
Dakovic-Rode,Oktavija
Kolaric,Branko
Vince,Adriana
Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
author_facet Mrzljak,Anna
Dinjar-Kujundzic,Petra
Vilibic-Cavlek,Tatjana
Jemersic,Lorena
Prpic,Jelena
Dakovic-Rode,Oktavija
Kolaric,Branko
Vince,Adriana
author_sort Mrzljak,Anna
title Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
title_short Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
title_full Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
title_fullStr Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
title_full_unstemmed Hepatitis E seroprevalence and associated risk factors in Croatian liver transplant recipients
title_sort hepatitis e seroprevalence and associated risk factors in croatian liver transplant recipients
description Abstract INTRODUCTION Solid-organ transplant recipients are at risk of hepatitis E virus (HEV) infection. We analyzed the seroprevalence/risk factors of HEV in Croatian liver transplant recipients. METHODS Two hundred forty-two serum samples were tested for HEV immunoglobuline IgG/IgM and HEV RNA. Sociodemographic data and risk factors were collected using a questionnaire. RESULTS HEV IgG seroprevalence rate was 24.4%. Positive/equivocal HEV IgM were found in two patients. HEV RNA was not detected. Logistic regression showed that older age, female gender, rural area/farm, water well, and septic tank were associated with HEV seropositivity. CONCLUSIONS This study revealed a high exposure rate to HEV in Croatian liver recipients.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 2019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100690
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