Pain and Quality of Life in Human T-cell Lymphotropic Virus Type 1-Associated Myelopathy or Tropical Spastic Paraparesis After Home-Based Exercise Protocol: A Randomized Clinical Trial
Abstract INTRODUCTION: Human T-cell lymphotropic virus type 1-associated myelopathy or tropical spastic paraparesis (HAM/TSP) causes, among other abnormalities, chronic pain that may impair quality of life (QOL). Home protocols can help those who have difficulty attending rehabilitation centers. This study aimed to evaluate the impact of a home-based exercise protocol on pain and QOL in people with HAM/TSP. METHODS: A randomized clinical trial of people with HAM/TSP (World Health Organization criteria) classified as probable or definite. The supervised group (SG) underwent training for 12 weeks and continued the protocol at home for another 12 weeks; the unsupervised group (UG) performed the same protocol at home without physical therapist supervision for 24 weeks; and the control group (CG) maintained the usual care. QOL was assessed by the Short Form-36 health survey and the pain condition by the Brief Pain Inventory (BPI). The Chi-square, analysis of variance, Kruskal-Wallis, and Friedman tests (5% alpha) were used for the analyses. The intention-to-treat method was adopted in case of follow-up losses. Record number RBR-849jyv/UTN: U1111-1176-2858. RESULTS: Of 56 participants, 49 completed the protocol. Mean pain was moderately reduced (>30%) in the UG and CG and mildly reduced (20%) in the SG. Loss in the vitality score of QOL in the CG was noted. CONCLUSIONS: The protocol generated mild and moderate pain relief and reduced losses in the functional QOL in the treatment groups.
Main Authors: | Macêdo,Maíra Carvalho, Mota,Renata de Sousa, Patrício,Naiane Araújo, Baptista,Abrahão Fontes, Andrade Filho,Antônio de Souza, Sá,Katia Nunes |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical - SBMT
2019
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100317 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Response to: RSBMT-2018-0270.R2 - Pain and quality of life in human T cell lymphotropic virus type 1 associated myelopathy or tropical spastic paraparesis after home-based exercise protocol: Randomized clinical trial
by: Macêdo,Maíra Carvalho, et al.
Published: (2022) -
Balance assessment in HTLV-1 associated myelopathy or tropical spastic paraparesis
by: Patrício,Naiane Araújo, et al.
Published: (2020) -
Possible etiologies for tropical spastic paraparesis and human T lymphotropic virus I-associated myelopathy
by: Zaninovic',V.
Published: (2004) -
Autoimmunity and molecular mimicry in tropical spastic paraparesis/human T-lymphotropic virus-associated myelopathy
by: García-Vallejo,F., et al.
Published: (2005) -
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients
by: Castro-Costa,Carlos Maurício de, et al.
Published: (2009)