Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case

Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.

Saved in:
Bibliographic Details
Main Authors: Gomes,Maria Antonia Ferreira, Medeiros,Lana Lira Cantidio de, Lobo,Fernanda Paula Dantas, Wanderley,Nathália Rayane Silva, Matos,Ana Paula Rodrigues, Jácome,Tácito do Nascimento, Monteiro,Maria Goretti Lins, Luz,Kleber Giovanni
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000300393
Tags: Add Tag
No Tags, Be the first to tag this record!