Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction
Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Brasileira de Medicina Tropical - SBMT
2014
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
oai:scielo:S0037-86822014000400533 |
|---|---|
| record_format |
ojs |
| spelling |
oai:scielo:S0037-868220140004005332014-11-28Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destructionAzulay-Abulafia,LunaSousa,Maria Auxiliadora JeunonPussanti,AndreaCoimbra,Daniel Dal'AstaVega,HernandoBernardes Filho,Fred Aspergillosis Aspergillus flavus Rhinosinusitis Cocaine addiction Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.47 n.4 20142014-08-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533en10.1590/0037-8682-0086-2014 |
| institution |
SCIELO |
| collection |
OJS |
| country |
Brasil |
| countrycode |
BR |
| component |
Revista |
| access |
En linea |
| databasecode |
rev-scielo-br |
| tag |
revista |
| region |
America del Sur |
| libraryname |
SciELO |
| language |
English |
| format |
Digital |
| author |
Azulay-Abulafia,Luna Sousa,Maria Auxiliadora Jeunon Pussanti,Andrea Coimbra,Daniel Dal'Asta Vega,Hernando Bernardes Filho,Fred |
| spellingShingle |
Azulay-Abulafia,Luna Sousa,Maria Auxiliadora Jeunon Pussanti,Andrea Coimbra,Daniel Dal'Asta Vega,Hernando Bernardes Filho,Fred Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| author_facet |
Azulay-Abulafia,Luna Sousa,Maria Auxiliadora Jeunon Pussanti,Andrea Coimbra,Daniel Dal'Asta Vega,Hernando Bernardes Filho,Fred |
| author_sort |
Azulay-Abulafia,Luna |
| title |
Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_short |
Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_full |
Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_fullStr |
Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_full_unstemmed |
Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_sort |
invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| description |
Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome. |
| publisher |
Sociedade Brasileira de Medicina Tropical - SBMT |
| publishDate |
2014 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533 |
| work_keys_str_mv |
AT azulayabulafialuna invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction AT sousamariaauxiliadorajeunon invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction AT pussantiandrea invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction AT coimbradanieldalasta invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction AT vegahernando invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction AT bernardesfilhofred invasiveaspergillosisinauserofinhaledcocainerhinosinusitiswithboneandcartilagedestruction |
| _version_ |
1756380536499077120 |