ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
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Main Authors: | MALLMANN,Eduardo José J., CUNHA,Francisco Afrânio, CASTRO,Bruno N.M.F., MACIEL,Auberson Martins, MENEZES,Everardo Albuquerque, FECHINE,Pierre Basílio Almeida |
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Format: | Digital revista |
Language: | English |
Published: |
Instituto de Medicina Tropical de São Paulo
2015
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652015000200165 |
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