Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy

Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy

A 64-year-old apparently immunocompetent white man developed lung and brain lesions of disseminated cryptococcosis. The radiologic features mimicked those of lung cancer metastatic to the central nervous system. C. gattii was recovered from cultures of bronchoalveolar lavage fluid, brain biopsy, and blood. The same fungus was recovered from pulmonary and brain specimens at autopsy. Serum and cerebrospinal fluid cryptococcal antigen tests were diagnostic in our case and should be included in the diagnostic evaluation of unexplained pulmonary and cerebral lesions. A literature search showed few reports of fungemia by this species of Cryptococcus, contrasting to C. neoformans.

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Main Authors: Oliveira,Flávio de Mattos, Severo,Cecília Bittencourt, Guazzelli,Luciana Silva, Severo,Luiz Carlos
Format: Digital revista
Language:English
Published: Instituto de Medicina Tropical de São Paulo 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652007000400014
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spelling oai:scielo:S0036-466520070004000142007-08-30Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancyOliveira,Flávio de MattosSevero,Cecília BittencourtGuazzelli,Luciana SilvaSevero,Luiz Carlos Fungemia Cryptococcosis Cryptococcus gattii A 64-year-old apparently immunocompetent white man developed lung and brain lesions of disseminated cryptococcosis. The radiologic features mimicked those of lung cancer metastatic to the central nervous system. C. gattii was recovered from cultures of bronchoalveolar lavage fluid, brain biopsy, and blood. The same fungus was recovered from pulmonary and brain specimens at autopsy. Serum and cerebrospinal fluid cryptococcal antigen tests were diagnostic in our case and should be included in the diagnostic evaluation of unexplained pulmonary and cerebral lesions. A literature search showed few reports of fungemia by this species of Cryptococcus, contrasting to C. neoformans.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.49 n.4 20072007-08-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652007000400014en10.1590/S0036-46652007000400014
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
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tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Oliveira,Flávio de Mattos
Severo,Cecília Bittencourt
Guazzelli,Luciana Silva
Severo,Luiz Carlos
spellingShingle Oliveira,Flávio de Mattos
Severo,Cecília Bittencourt
Guazzelli,Luciana Silva
Severo,Luiz Carlos
Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
author_facet Oliveira,Flávio de Mattos
Severo,Cecília Bittencourt
Guazzelli,Luciana Silva
Severo,Luiz Carlos
author_sort Oliveira,Flávio de Mattos
title Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
title_short Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
title_full Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
title_fullStr Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
title_full_unstemmed Cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
title_sort cryptococcus gattii fungemia: report of a case with lung and brain lesions mimicking radiological features of malignancy
description A 64-year-old apparently immunocompetent white man developed lung and brain lesions of disseminated cryptococcosis. The radiologic features mimicked those of lung cancer metastatic to the central nervous system. C. gattii was recovered from cultures of bronchoalveolar lavage fluid, brain biopsy, and blood. The same fungus was recovered from pulmonary and brain specimens at autopsy. Serum and cerebrospinal fluid cryptococcal antigen tests were diagnostic in our case and should be included in the diagnostic evaluation of unexplained pulmonary and cerebral lesions. A literature search showed few reports of fungemia by this species of Cryptococcus, contrasting to C. neoformans.
publisher Instituto de Medicina Tropical de São Paulo
publishDate 2007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652007000400014
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AT severoceciliabittencourt cryptococcusgattiifungemiareportofacasewithlungandbrainlesionsmimickingradiologicalfeaturesofmalignancy
AT guazzellilucianasilva cryptococcusgattiifungemiareportofacasewithlungandbrainlesionsmimickingradiologicalfeaturesofmalignancy
AT severoluizcarlos cryptococcusgattiifungemiareportofacasewithlungandbrainlesionsmimickingradiologicalfeaturesofmalignancy
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