Is Demodex really non-pathogenic?

Although usually considered a non-pathogenic parasite in parasitological textbooks, Demodex folliculorum has been implicated as a causative agent for some dermatological conditions, such as rosacea-like eruptions and some types of blepharitis. Several anecdotal reports have demonstrated unequivocal tissue damage directly related to the presence of the parasite. However, this seems to be exceedingly rare, in contrast with the marked prevalence of this infestation. We have had the opportunity to observe one of such cases. A 38-year-old woman presented with rosacea-like papular lesions in her right cheek. Histopathological examination revealed granulomatous dermal inflammation with a well-preserved mite phagocytized by a multinucleated giant cell. This finding may be taken as an evidence for the pathogenicity of the parasite, inasmuch as it does not explain how such a common parasite is able to produce such a rare disease.

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Autores principales: PENA,Gil Patrus, ANDRADE FILHO,José de Souza
Formato: Digital revista
Idioma:English
Publicado: Instituto de Medicina Tropical de São Paulo 2000
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652000000300012
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spelling oai:scielo:S0036-466520000003000122000-07-24Is Demodex really non-pathogenic?PENA,Gil PatrusANDRADE FILHO,José de Souza Demodex Skin diseases Host-parasite relationship Although usually considered a non-pathogenic parasite in parasitological textbooks, Demodex folliculorum has been implicated as a causative agent for some dermatological conditions, such as rosacea-like eruptions and some types of blepharitis. Several anecdotal reports have demonstrated unequivocal tissue damage directly related to the presence of the parasite. However, this seems to be exceedingly rare, in contrast with the marked prevalence of this infestation. We have had the opportunity to observe one of such cases. A 38-year-old woman presented with rosacea-like papular lesions in her right cheek. Histopathological examination revealed granulomatous dermal inflammation with a well-preserved mite phagocytized by a multinucleated giant cell. This finding may be taken as an evidence for the pathogenicity of the parasite, inasmuch as it does not explain how such a common parasite is able to produce such a rare disease.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.42 n.3 20002000-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652000000300012en10.1590/S0036-46652000000300012
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author PENA,Gil Patrus
ANDRADE FILHO,José de Souza
spellingShingle PENA,Gil Patrus
ANDRADE FILHO,José de Souza
Is Demodex really non-pathogenic?
author_facet PENA,Gil Patrus
ANDRADE FILHO,José de Souza
author_sort PENA,Gil Patrus
title Is Demodex really non-pathogenic?
title_short Is Demodex really non-pathogenic?
title_full Is Demodex really non-pathogenic?
title_fullStr Is Demodex really non-pathogenic?
title_full_unstemmed Is Demodex really non-pathogenic?
title_sort is demodex really non-pathogenic?
description Although usually considered a non-pathogenic parasite in parasitological textbooks, Demodex folliculorum has been implicated as a causative agent for some dermatological conditions, such as rosacea-like eruptions and some types of blepharitis. Several anecdotal reports have demonstrated unequivocal tissue damage directly related to the presence of the parasite. However, this seems to be exceedingly rare, in contrast with the marked prevalence of this infestation. We have had the opportunity to observe one of such cases. A 38-year-old woman presented with rosacea-like papular lesions in her right cheek. Histopathological examination revealed granulomatous dermal inflammation with a well-preserved mite phagocytized by a multinucleated giant cell. This finding may be taken as an evidence for the pathogenicity of the parasite, inasmuch as it does not explain how such a common parasite is able to produce such a rare disease.
publisher Instituto de Medicina Tropical de São Paulo
publishDate 2000
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652000000300012
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