Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018

Background: The presence of toxic metals in human populations is strongly associated with chronic diseases. Aim: To determine levels of lead, chromium, cadmium, mercury and inorganic arsenic (AsIn) in the general population aged over 5 years in Antofagasta, Chile. Material and Methods: People living in Urban Antofagasta for at least five years were considered eligible. Biological samples were obtained to measure heavy metals. Results: One thousand two hundred three participants with a median age of 43 years (656 women) were studied. Their mean time of residence in the city was 30 years, and 52% smoked. Eight percent of the adult population and 12% of children had AsIn values above 35 µg/L, while 75% of the population had levels below 21.9 µg/L. The other metals were below the risk levels defined by the health authority (10 µg/L for chromium, 10 µg/L for mercury, 2 µg/L for cadmium, 5 and 10 μg/dL for blood lead for children and adults, respectively). The factors associated with high levels of AsIn in adults were male sex, living more than 200 meters from monitoring points, and low schooling. In children, the associated variables were high intake of seafood products and having a caregiver with less than 8 years of schooling. Contrary to expectations, the greatest risk of presenting altered levels of the metals occurred in the population living more than 500 meters from the identified risk sources (90% of the population). Conclusions: The findings of this study suggest that all potential sources of exposure to AsIn should be evaluated, and surveillance actions should be established to reduce involuntary exposure to this metalloid.

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Main Authors: Ríos,Juan Carlos, Villarroel,Luis, Torres,Marisa, Astaburuaga,Juan Pablo, Leiva,Cinthya, Cook,Paz, Medel,Patricio, Cortés,Sandra
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2020
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600746
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spelling oai:scielo:S0034-988720200006007462020-09-29Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018Ríos,Juan CarlosVillarroel,LuisTorres,MarisaAstaburuaga,Juan PabloLeiva,CinthyaCook,PazMedel,PatricioCortés,Sandra Arsenicals Chile Lead Metals, Heavy Urine Background: The presence of toxic metals in human populations is strongly associated with chronic diseases. Aim: To determine levels of lead, chromium, cadmium, mercury and inorganic arsenic (AsIn) in the general population aged over 5 years in Antofagasta, Chile. Material and Methods: People living in Urban Antofagasta for at least five years were considered eligible. Biological samples were obtained to measure heavy metals. Results: One thousand two hundred three participants with a median age of 43 years (656 women) were studied. Their mean time of residence in the city was 30 years, and 52% smoked. Eight percent of the adult population and 12% of children had AsIn values above 35 µg/L, while 75% of the population had levels below 21.9 µg/L. The other metals were below the risk levels defined by the health authority (10 µg/L for chromium, 10 µg/L for mercury, 2 µg/L for cadmium, 5 and 10 μg/dL for blood lead for children and adults, respectively). The factors associated with high levels of AsIn in adults were male sex, living more than 200 meters from monitoring points, and low schooling. In children, the associated variables were high intake of seafood products and having a caregiver with less than 8 years of schooling. Contrary to expectations, the greatest risk of presenting altered levels of the metals occurred in the population living more than 500 meters from the identified risk sources (90% of the population). Conclusions: The findings of this study suggest that all potential sources of exposure to AsIn should be evaluated, and surveillance actions should be established to reduce involuntary exposure to this metalloid.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.6 20202020-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600746es10.4067/S0034-98872020000600746
institution SCIELO
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country Chile
countrycode CL
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databasecode rev-scielo-cl
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region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Ríos,Juan Carlos
Villarroel,Luis
Torres,Marisa
Astaburuaga,Juan Pablo
Leiva,Cinthya
Cook,Paz
Medel,Patricio
Cortés,Sandra
spellingShingle Ríos,Juan Carlos
Villarroel,Luis
Torres,Marisa
Astaburuaga,Juan Pablo
Leiva,Cinthya
Cook,Paz
Medel,Patricio
Cortés,Sandra
Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
author_facet Ríos,Juan Carlos
Villarroel,Luis
Torres,Marisa
Astaburuaga,Juan Pablo
Leiva,Cinthya
Cook,Paz
Medel,Patricio
Cortés,Sandra
author_sort Ríos,Juan Carlos
title Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
title_short Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
title_full Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
title_fullStr Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
title_full_unstemmed Estudio de metales urinarios y plomo en sangre: parámetros poblacionales en Antofagasta, 2018
title_sort estudio de metales urinarios y plomo en sangre: parámetros poblacionales en antofagasta, 2018
description Background: The presence of toxic metals in human populations is strongly associated with chronic diseases. Aim: To determine levels of lead, chromium, cadmium, mercury and inorganic arsenic (AsIn) in the general population aged over 5 years in Antofagasta, Chile. Material and Methods: People living in Urban Antofagasta for at least five years were considered eligible. Biological samples were obtained to measure heavy metals. Results: One thousand two hundred three participants with a median age of 43 years (656 women) were studied. Their mean time of residence in the city was 30 years, and 52% smoked. Eight percent of the adult population and 12% of children had AsIn values above 35 µg/L, while 75% of the population had levels below 21.9 µg/L. The other metals were below the risk levels defined by the health authority (10 µg/L for chromium, 10 µg/L for mercury, 2 µg/L for cadmium, 5 and 10 μg/dL for blood lead for children and adults, respectively). The factors associated with high levels of AsIn in adults were male sex, living more than 200 meters from monitoring points, and low schooling. In children, the associated variables were high intake of seafood products and having a caregiver with less than 8 years of schooling. Contrary to expectations, the greatest risk of presenting altered levels of the metals occurred in the population living more than 500 meters from the identified risk sources (90% of the population). Conclusions: The findings of this study suggest that all potential sources of exposure to AsIn should be evaluated, and surveillance actions should be established to reduce involuntary exposure to this metalloid.
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000600746
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