Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile

Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 fig/dl, compared with those that had a lead level below 43 fig/dl (86.7±7.3 and 93±11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects aged ¡ess than six years at the moment of lead exposure had a lower IQ when assessed ten years later.

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Main Authors: Coria,Carolina, Cabello,Aurora, Tassara,Enzo, López,Eduardo, Rosales,Hugo, Pérez,Marcelo, Zavala,Claudia, Muñoz,Patricio, Orellana,Gabriel, lnostroza,María Isabel, Contreras,Lorena, Kirsten,Lilian
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2009
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800006
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spelling oai:scielo:S0034-988720090008000062009-11-04Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de ChileCoria,CarolinaCabello,AuroraTassara,EnzoLópez,EduardoRosales,HugoPérez,MarceloZavala,ClaudiaMuñoz,PatricioOrellana,Gabriellnostroza,María IsabelContreras,LorenaKirsten,Lilian Intelligence Lead poisoning nervous system Neurotoxicity syndromes Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 fig/dl, compared with those that had a lead level below 43 fig/dl (86.7±7.3 and 93±11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects aged ¡ess than six years at the moment of lead exposure had a lower IQ when assessed ten years later.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.8 20092009-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800006es10.4067/S0034-98872009000800006
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
tag revista
region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Coria,Carolina
Cabello,Aurora
Tassara,Enzo
López,Eduardo
Rosales,Hugo
Pérez,Marcelo
Zavala,Claudia
Muñoz,Patricio
Orellana,Gabriel
lnostroza,María Isabel
Contreras,Lorena
Kirsten,Lilian
spellingShingle Coria,Carolina
Cabello,Aurora
Tassara,Enzo
López,Eduardo
Rosales,Hugo
Pérez,Marcelo
Zavala,Claudia
Muñoz,Patricio
Orellana,Gabriel
lnostroza,María Isabel
Contreras,Lorena
Kirsten,Lilian
Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
author_facet Coria,Carolina
Cabello,Aurora
Tassara,Enzo
López,Eduardo
Rosales,Hugo
Pérez,Marcelo
Zavala,Claudia
Muñoz,Patricio
Orellana,Gabriel
lnostroza,María Isabel
Contreras,Lorena
Kirsten,Lilian
author_sort Coria,Carolina
title Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
title_short Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
title_full Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
title_fullStr Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
title_full_unstemmed Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile
title_sort efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de chile
description Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 fig/dl, compared with those that had a lead level below 43 fig/dl (86.7±7.3 and 93±11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects aged ¡ess than six years at the moment of lead exposure had a lower IQ when assessed ten years later.
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800006
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