Refractory epilepsy in children with brain tumors. The urgency of neurosurgery
ABSTRACT In order to verify indications for surgery, 27 patients with refractory epileptic seizures and brain tumor, aged up to 19 years at the time of surgery, were studied between 1996 and 2013 and followed up for at least one year. The mean interval between the onset of seizures and the diagnosis of the tumor was 3.6 years, and from diagnosis to the surgery, 18 months. The location of the tumor was in the temporal lobe in 16, with ganglioglioma and dysembryoplastic neuroepithelial tumors being the most frequent. Among the patients, 92.5% and 90.4% were seizure-free in the first and fifth year after surgery, respectively. Twelve of 16 children were successful in becoming drug-free, with complete withdrawal by 3.2 years. Surgery proved to be potentially curative and safe in these cases, suggesting that the tumor diagnosis and surgery cannot be postponed.
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Academia Brasileira de Neurologia - ABNEURO
2016
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oai:scielo:S0004-282X20160012010082017-04-24Refractory epilepsy in children with brain tumors. The urgency of neurosurgeryBernardino,Marília Rosa AbtibolFunayama,CarolinaHamad,Ana Paula AndradeMachado,HélioSakamoto,AméricoThome,UrsulaTerra,Vera CristinaSantos,Antonio Carlos dosSerafani,Luciano NaderCalixto,Nathalia CunhaSilva,Huria Shalom Monturil de Carvalho brain neoplasms epilepsy child adolescent neurosurgery ABSTRACT In order to verify indications for surgery, 27 patients with refractory epileptic seizures and brain tumor, aged up to 19 years at the time of surgery, were studied between 1996 and 2013 and followed up for at least one year. The mean interval between the onset of seizures and the diagnosis of the tumor was 3.6 years, and from diagnosis to the surgery, 18 months. The location of the tumor was in the temporal lobe in 16, with ganglioglioma and dysembryoplastic neuroepithelial tumors being the most frequent. Among the patients, 92.5% and 90.4% were seizure-free in the first and fifth year after surgery, respectively. Twelve of 16 children were successful in becoming drug-free, with complete withdrawal by 3.2 years. Surgery proved to be potentially curative and safe in these cases, suggesting that the tumor diagnosis and surgery cannot be postponed.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.74 n.12 20162016-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001201008en10.1590/0004-282x20160157 |
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Bernardino,Marília Rosa Abtibol Funayama,Carolina Hamad,Ana Paula Andrade Machado,Hélio Sakamoto,Américo Thome,Ursula Terra,Vera Cristina Santos,Antonio Carlos dos Serafani,Luciano Nader Calixto,Nathalia Cunha Silva,Huria Shalom Monturil de Carvalho |
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Bernardino,Marília Rosa Abtibol Funayama,Carolina Hamad,Ana Paula Andrade Machado,Hélio Sakamoto,Américo Thome,Ursula Terra,Vera Cristina Santos,Antonio Carlos dos Serafani,Luciano Nader Calixto,Nathalia Cunha Silva,Huria Shalom Monturil de Carvalho Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
author_facet |
Bernardino,Marília Rosa Abtibol Funayama,Carolina Hamad,Ana Paula Andrade Machado,Hélio Sakamoto,Américo Thome,Ursula Terra,Vera Cristina Santos,Antonio Carlos dos Serafani,Luciano Nader Calixto,Nathalia Cunha Silva,Huria Shalom Monturil de Carvalho |
author_sort |
Bernardino,Marília Rosa Abtibol |
title |
Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
title_short |
Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
title_full |
Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
title_fullStr |
Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
title_full_unstemmed |
Refractory epilepsy in children with brain tumors. The urgency of neurosurgery |
title_sort |
refractory epilepsy in children with brain tumors. the urgency of neurosurgery |
description |
ABSTRACT In order to verify indications for surgery, 27 patients with refractory epileptic seizures and brain tumor, aged up to 19 years at the time of surgery, were studied between 1996 and 2013 and followed up for at least one year. The mean interval between the onset of seizures and the diagnosis of the tumor was 3.6 years, and from diagnosis to the surgery, 18 months. The location of the tumor was in the temporal lobe in 16, with ganglioglioma and dysembryoplastic neuroepithelial tumors being the most frequent. Among the patients, 92.5% and 90.4% were seizure-free in the first and fifth year after surgery, respectively. Twelve of 16 children were successful in becoming drug-free, with complete withdrawal by 3.2 years. Surgery proved to be potentially curative and safe in these cases, suggesting that the tumor diagnosis and surgery cannot be postponed. |
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Academia Brasileira de Neurologia - ABNEURO |
publishDate |
2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001201008 |
work_keys_str_mv |
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