Motor assessment in patients with Duchenne muscular dystrophy

OBJECTIVE: Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months. METHOD: Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Function Measure (MFM). The patients were evaluated twice within a six-month interval. RESULTS: Loss of muscle strength was identified in the MRC score for upper proximal members (t=-2.17, p=0.04). In the MFM, it was noted significant loss in the dimension 1 (t=-3.06, p=0.006). Moderate and strong correlations were found between the scores for muscular strength and the MFM dimensions. CONCLUSION: The MFM scale was a useful instrument in the follow up of patients with DMD. Moreover, it is a more comprehensive scale to assess patients and very good for conducting trials to evaluate treatment.

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Main Authors: Diniz,Gabriela Palhares Campolina, Lasmar,Laura Maria de Lima Belizário Facury, Giannetti,Juliana Gurgel
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000600007
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spelling oai:scielo:S0004-282X20120006000072012-06-11Motor assessment in patients with Duchenne muscular dystrophyDiniz,Gabriela Palhares CampolinaLasmar,Laura Maria de Lima Belizário FacuryGiannetti,Juliana Gurgel Duchenne muscular dystrophy motor function measure medical research council OBJECTIVE: Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months. METHOD: Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Function Measure (MFM). The patients were evaluated twice within a six-month interval. RESULTS: Loss of muscle strength was identified in the MRC score for upper proximal members (t=-2.17, p=0.04). In the MFM, it was noted significant loss in the dimension 1 (t=-3.06, p=0.006). Moderate and strong correlations were found between the scores for muscular strength and the MFM dimensions. CONCLUSION: The MFM scale was a useful instrument in the follow up of patients with DMD. Moreover, it is a more comprehensive scale to assess patients and very good for conducting trials to evaluate treatment.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.70 n.6 20122012-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000600007en10.1590/S0004-282X2012000600007
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countrycode BR
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libraryname SciELO
language English
format Digital
author Diniz,Gabriela Palhares Campolina
Lasmar,Laura Maria de Lima Belizário Facury
Giannetti,Juliana Gurgel
spellingShingle Diniz,Gabriela Palhares Campolina
Lasmar,Laura Maria de Lima Belizário Facury
Giannetti,Juliana Gurgel
Motor assessment in patients with Duchenne muscular dystrophy
author_facet Diniz,Gabriela Palhares Campolina
Lasmar,Laura Maria de Lima Belizário Facury
Giannetti,Juliana Gurgel
author_sort Diniz,Gabriela Palhares Campolina
title Motor assessment in patients with Duchenne muscular dystrophy
title_short Motor assessment in patients with Duchenne muscular dystrophy
title_full Motor assessment in patients with Duchenne muscular dystrophy
title_fullStr Motor assessment in patients with Duchenne muscular dystrophy
title_full_unstemmed Motor assessment in patients with Duchenne muscular dystrophy
title_sort motor assessment in patients with duchenne muscular dystrophy
description OBJECTIVE: Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months. METHOD: Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Function Measure (MFM). The patients were evaluated twice within a six-month interval. RESULTS: Loss of muscle strength was identified in the MRC score for upper proximal members (t=-2.17, p=0.04). In the MFM, it was noted significant loss in the dimension 1 (t=-3.06, p=0.006). Moderate and strong correlations were found between the scores for muscular strength and the MFM dimensions. CONCLUSION: The MFM scale was a useful instrument in the follow up of patients with DMD. Moreover, it is a more comprehensive scale to assess patients and very good for conducting trials to evaluate treatment.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000600007
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AT lasmarlauramariadelimabelizariofacury motorassessmentinpatientswithduchennemusculardystrophy
AT giannettijulianagurgel motorassessmentinpatientswithduchennemusculardystrophy
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